摘要
阐述了轮状病毒感染继发婴幼儿乳糖不耐受的病理机制是乳糖酶缺乏和肠道菌群失调,治疗方案包括接种病毒疫苗、应用乳糖酶、益生菌制剂、中药及辅助对症治疗等。目前,对本病尚无稳定的相关的实验模型,也就缺乏明确的公认的评价指标,这对研究相关药物、开发新药来讲都是一个瓶颈。
It was explained that pathological mechanism of infantile lactase intolerance secondary to rotavirus infection was lack of lactase and imbalance of intestinal flora.The treatment includes rotavirus vaccine,lactase,probiotics,traditional Chinese medicine and auxiliary treatments.There were no suitable trial models for the disease,thus lacking specific and generally accepted evaluation indexes.It was a bottleneck for developing interrelated medicines.
出处
《中医儿科杂志》
2013年第5期57-59,共3页
Journal of Pediatrics of Traditional Chinese Medicine
基金
江苏省高校自然科学研究项目(12KJD360004)
南京中医药大学科技创新风险基金项目(CX201203)
关键词
乳糖不耐受
轮状病毒
婴幼儿
病理机制
治疗
lactose intolerance
rotavirus
infants
pathological mechanism
treatment