摘要
目的探讨儿童多发性大动脉炎(TA)的临床特征及治疗转归。方法回顾性分析12例儿童多发性大动脉炎患儿的临床表现、治疗过程及预后。结果患儿发病年龄为1.5~14岁,男女比例为1∶2。临床主要表现为发热、头痛、高血压、血管杂音、血沉快、C反应蛋白升高,其中8例有结核感染;临床分型以Ⅰ型最多,有6例(50%);12例患儿接受糖皮质激素和甲氨蝶呤治疗后,11例病情缓解。结论儿童多发性大动脉炎临床症状不典型,应进行全面细致的体格检查,尤其注意四肢血压、脉搏及血管杂音情况,避免漏诊,早期诊断是提高治疗效果的关键。
Objective To investigate clinical features and treatment effect of polyarteritis.Methods The clinical manifestations,treatment and prognosis of 12 cases of polyarteritis were reviewed.Results The onset age was 1.5 ~ 14 years old.The ratio of male to female was 1 ∶ 2.The main clinical manifestations were fever,headache,hypertension,vascular murmur,fast ESR,increased C reaction protein.8 cases were infected with tuberculosis.6 cases belong to type I(50%);12 patients received corticosteroids and methotrexate treatment,11 cases got remission.Conclusion Clinical symptoms of polyarteritis are not typical.Physical examination should be careful,especially blood pressure,pulse and vascular murmur in the limbs,in order to avoid missed diagnosis.Early diagnosis is the key to improve the effect of treatment.
出处
《中医儿科杂志》
2013年第5期32-34,共3页
Journal of Pediatrics of Traditional Chinese Medicine