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儿童多发性大动脉炎12例临床分析 被引量:1

Clinical analysis of 12 cases of pediatric polyarteritis
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摘要 目的探讨儿童多发性大动脉炎(TA)的临床特征及治疗转归。方法回顾性分析12例儿童多发性大动脉炎患儿的临床表现、治疗过程及预后。结果患儿发病年龄为1.5~14岁,男女比例为1∶2。临床主要表现为发热、头痛、高血压、血管杂音、血沉快、C反应蛋白升高,其中8例有结核感染;临床分型以Ⅰ型最多,有6例(50%);12例患儿接受糖皮质激素和甲氨蝶呤治疗后,11例病情缓解。结论儿童多发性大动脉炎临床症状不典型,应进行全面细致的体格检查,尤其注意四肢血压、脉搏及血管杂音情况,避免漏诊,早期诊断是提高治疗效果的关键。 Objective To investigate clinical features and treatment effect of polyarteritis.Methods The clinical manifestations,treatment and prognosis of 12 cases of polyarteritis were reviewed.Results The onset age was 1.5 ~ 14 years old.The ratio of male to female was 1 ∶ 2.The main clinical manifestations were fever,headache,hypertension,vascular murmur,fast ESR,increased C reaction protein.8 cases were infected with tuberculosis.6 cases belong to type I(50%);12 patients received corticosteroids and methotrexate treatment,11 cases got remission.Conclusion Clinical symptoms of polyarteritis are not typical.Physical examination should be careful,especially blood pressure,pulse and vascular murmur in the limbs,in order to avoid missed diagnosis.Early diagnosis is the key to improve the effect of treatment.
出处 《中医儿科杂志》 2013年第5期32-34,共3页 Journal of Pediatrics of Traditional Chinese Medicine
关键词 儿童 多发性大动脉炎 临床分析 children polyarteritis clinical analysis
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参考文献5

  • 1Maksimowicz M K,Clark T M,Hoffman G S.Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients[J].Arthritis Rheum,2007,56(3):1000-1009.
  • 2丛晓亮,赵仙先.多发性大动脉炎治疗进展[J].新医学,2009,40(5):331-333. 被引量:14
  • 3Schmidt W A.Takaynsu and temporal arteritis[J].Front Neurol Neurosci,2006,21:96-104.
  • 4Karageorgaxiz T,Mavragani C P,Papathanasiou M A,et al.Infliximab in Takayasu arteritis:a safe alternative?[J].Clin Rheumatol,2007,26(6):984-987.
  • 5李彩凤.多发性大动脉炎的诊治与预后[J].中国小儿急救医学,2009,16(5):423-425. 被引量:5

二级参考文献21

  • 1MAKSIMOWICZ-MCKINNON K, CLARK T M, HOFFMAN G S. Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients [J]. Arthritis Rheum, 2007, 56 (3): 1000-1009.
  • 2VANOLI M, DAINA E, SALVARANI C, et al. Takayasu's arteritis: a study of 104 Italian patients[J]. Arthritis Rheum, 2005, 53 (1) : 100-107.
  • 3DE FRANCISCIS S, SERRA R, LUONGO A, et al. The management of Takayasu' s arteritis : personal experience [ J]. Ann Vasc Surg, 2007, 21 (6) : 754-760.
  • 4MOLLOY E S, LANGFORD C A, CLARK T M, et al. Anti-tumour necrosis factor therapy in patients with refractory Takayasu arteritis : long-term follow-up [J]. Ann Rheum Dis, 2008, 67 (11) : 1567-1569.
  • 5KARAGEORGAKI Z T, MAVRAGANI C P, PAPATHANASIOU M A, et al. Infliximab in Takayasu arteritis: a safe alternative? [ J ] Clin Rheumatol, 2007, 26 (6): 984-987.
  • 6LARSSON K, NORDBORG C, MOSLEMI A R, et al. A Western blot and molecular genetic investigation of the estrogen receptor beta in giant cell arteritis[J]. Clin Exp Rheumatol, 2006, 24 (2 Suppl 41): S17-S19.
  • 7NESHER G, BERKUN Y, MATES M, et al. Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis [J]. Arthritis Rheum, 2004, 50 (4) : 1332-1337.
  • 8SCHMIDT W A. Takayasu and temporal arteritis [J]. Front Neurol Neurosci, 2006, 21 : 96-104.
  • 9MORO J A, ALMENAR L, MARTINEZ-DOLZ L, et al. Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation [J]. Transplant Proc, 2005, 40 (9) : 3034-3036.
  • 10FIELDS C E, BOWER T C, COOPER L T, et al. Takayasu's arteritis: operative results and influence of disease activity[J]. J Vasc Surg, 2006, 43 (1) : 64- 71.

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