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未足月胎膜早破390例期待疗法时间及终止妊娠时机分析 被引量:6

Expectant Treatment Time and Timing of Pregnancy Termination in Preterm Premature Rupture of Membranes: an Analysis of 390 Cases
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摘要 目的探讨未足月胎膜早破期待疗法时间及终止妊娠时机的选择,以降低围生儿死亡率。方法回顾性分析390例未足月胎膜早破患者的临床资料,其中孕周28-33辐周138例,孕周34-36柏周252例。对无临床感染征象或其他产科并发症者,采用保守治疗延长孕周;对于胎肺已成熟或有宫内感染、胎儿窘迫等终止妊娠指征者终止妊娠。结果孕周28-33“周新生儿窒息、感染、颅内出血、围生儿死亡、新生儿呼吸窘迫综合征发生率明显高于孕周34-36“周(均P〈0.05)。结论胎膜早破期待疗法时间及终止妊娠时机根据孕周及母婴情况而定。 Objective To investigate the time of expectant therapy and timing of pregnancy termination in preterm premature rupture of the membranes (PPROM) for reducing perinatal mortality. Methods A retrospective analysis was performed in 138 patients with PPROM at 28 to 33~ weeks of gestation and 252 patients with PPROM at 34 to 36^+6 weeks of gestation. Conservative treatment was given to extend gestational age in patients without clinical infection signs or other obstetric complications. The pregnancy was terminated in patients with fetal lung maturity, intrauterine infection, fetal distress or other indications. Results Incidences of neonatal asphyxia, infection, intracranial hemorrhage, perinatal death and neonatal respiratory distress syndrome in patients with PPROM at 28 to 33^+6 weeks of gestation were significantly higher than those in patients with PPROM at 34 to 36^+6 weeks of gestation (P 〈0.05) .Conclusion Expectant treatment time and timing of pregnancy termination should be selected according to gestational age and maternal and infant condition.
出处 《实用临床医学(江西)》 CAS 2013年第8期51-52,75,共3页 Practical Clinical Medicine
关键词 未足月胎膜早破 期待疗法 终止妊娠 preterm premature rupture of the membranes expectant therapy pregnancy termination
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