摘要
目的 评价意识指数（IoC）监测小儿吸入七氟醚麻醉深度的准确性.方法 择期全麻下行腹部手术患儿42例,ASA分级Ⅰ级或Ⅱ级,性别不限,年龄8～ 12岁.吸入七氟醚麻醉诱导气管插管后,调节吸入七氟醚的浓度,分别维持呼气末七氟醚浓度（CET Sev） 1.6％、2.1％、2.6％、3.1％、3.6％、4.1％和4.6％5 min,同步记录IoC值和BIS值.结果 CET Sev＜ 3.1％时,其与IoC值、BIS值均呈负相关,相关系数分别为-0.927（r1）、-0.869 （r2）（P＜ 0.01）；CETSev 3.1％ ～ 4.6％时,其与IoC值、BIS值均呈负相关,相关系数分别-0.808（r3,P＜0.01）、-0.430 （r4,P＜0.05）.相关系数绝对值比较：r1、r2及r3间比较差异无统计学意义（P＞0.05）,r1、r2、r3均大于r4（P ＜0.01）.结论 IoC能准确反映小儿吸入七氟醚的麻醉深度；CETSev 3.1％ ～ 4.6％时,IoC监测其麻醉深度的准确性优于BIS.
Objective To evaluate the accuracy of the index of consciousness （IoC） in monitoring the depth of anesthesia with sevoflurane inhalation in children,by comparing it with the bispectral index （BIS）.Methods Forty-two ASA physical status Ⅰ or Ⅱ children,aged 8-12 yr,scheduled for elective abdominal surgery under general anesthesia,were studied.Anesthesia was induced with sevoflurane inhalation.The patients were endotracheally intubated.The concentration of sevoflurane was then adjusted to maintain the end-tidal concentration of sevoflurane （CETSev） at 1.6%,2.1%,2.6%,3.1%,3.6%,4.1% and 4.6% for5 min.The IoC and BIS values were recorded simultaneously.Results When CETSev 〈 3.1%,CETSev was negatively correlated with IoC and BIS values,and the correlation coefficients between CETSev and IoC and BIS values were-0.927 （r1） and -0.869 （r2）,respectively （P 〈 0.01）.When 3.1% ≤ CETSev ≤ 4.6 %,CET Sev was negatively correlated with IoC and BIS values,and the correlation coefficients between CETSev and IoC and BIS values were-0.808 （r3,P〈 0.01） and-0.430 （r4,P 〈 0.05）,respectively.Comparison of the absolute value of correlation coefficients：there was no significant difference between r1,r2 and r3 （P 〉 0.05） ; r1,r2 and r3 were significantly larger than r4 （P 〈 0.01）.Conclusion IoC can accurately reflect the depth of anesthesia with sevoflurane inhalation in children and when 3.1% ≤ CET Sev ≤ 4.6 %,the accuracy of IoC in monitoring the depth of anesthesia is superior to that of BIS. Keywords：Monitoring, intraoperative; Anesthetics, inhalation; Electrical trace technique; Children
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
2013年第9期1047-1049,共3页
Chinese Journal of Anesthesiology
关键词
监测
手术中
麻醉药
吸入
脑电描记术
儿童
Monitoring, intraoperative
Anesthetics, inhalation
Electrical trace technique
Children
