摘要
戊型肝炎病毒(HEV)体外细胞培养模型的建立有助于阐明HEV的感染、复制及其致病机理,有利于新型抗病毒药物和疫苗的研发与评估。近年来国内外对HEV细胞培养模型的报道很多,但所用细胞系、感染方法及病毒的复制效果等不尽相同。因此,对近年来HEV细胞培养模型的研究进展进行了综述。
The development of cell culture models for hepatitis E virus （ HEV） in vitro can help to elucidate the mecha-nisms for HEV infection , replication and pathogenesis , thus promoting the development and evaluation of new antivirus agents and vaccines.In recent years, many studies on HEV cell culture models have been reported , however, these studies showed differences in the cell lines , infecting methods and viral replication effects .This review summarizes the progress on HEV cell culture models .
出处
《微生物学免疫学进展》
2013年第5期42-46,共5页
Progress In Microbiology and Immunology
基金
国家自然科学基金资助项目(81271827)
高等学校博士学科点专项科研基金课题(20120001110098)
