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小儿会阴型尿道下裂手术中吸入全麻诱导前右美托咪啶的应用观察 被引量:3

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摘要 目的观察喉罩吸入全麻诱导前应用右美托咪啶对会阴型尿道下裂手术患儿麻醉深度及苏醒质量的影响。方法择期行会阴型尿道下裂手术男性患儿40例,随机分成右美托咪啶组(D组)和对照组(C组)。D组给予右美托咪啶负荷剂量1μg/kg,10 min注射完毕,术中以0.5μg/(kg·h)维持输注;C组静脉输注相同剂量生理盐水,之后静脉全麻诱导,行喉罩吸入全麻。记录给药前(T0),诱导后置入喉罩前(T1),置入喉罩后1 min(T2)、5min(T3),手术结束时(T4),清醒睁眼时(T5),拔出喉罩后1 min(T6)、5 min(T7)、10 min(T8)患儿的心率(HR)、收缩压(SBP)、舒张压(DBP)。并记录患儿停药至清醒睁眼时间、拔出喉罩时间及不良反应。结果两组HR、SBP及DBP在T1、T2、T3、T4时点差异无统计学意义。与C组相比,D组SBP、DBP及HR在T5、T6时点下降,且停药至清醒睁眼时间、拔出喉罩时间缩短(P均<0.05)。两组均未见严重不良反应。结论喉罩吸入全麻诱导前应用右美托咪啶可减少拔管反应和苏醒期不良反应,提高围术期血流动力学稳定性,使喉罩全麻会阴型尿道下裂手术患儿麻醉镇静深度适当。
出处 《山东医药》 CAS 2013年第39期83-84,共2页 Shandong Medical Journal
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参考文献11

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二级参考文献22

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