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肌钙蛋白自身抗体与心血管疾病 被引量：3

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摘要 自身免疫在许多心血管疾病的发病机制中起到关键作用,如扩张型心肌病、心肌炎、风湿热和动脉粥样硬化性心脏病。心肌损伤后暴露自身抗原,可能会引发自身免疫反应,一些心脏病患者中可检测到心肌自身抗体,某些健康个体中也可检测到低滴度心肌自身抗体。肌钙蛋白(TnI)是心肌损伤的特异性标志物,在扩张型心肌病及缺血性心肌病患者中可检测到抗-TnI抗体。急性冠脉综合征患者中,抗-TnI抗体的出现可能导致TnI假阴性结果而延误治疗时机。抗-TnI抗体在疾病发病机制中的作用尚未阐明,该文就TnI抗体在心肌病、心肌炎、急性冠脉综合征及心肌梗死后心衰中的作用加以综述。
作者 郭素箴 卢成志
机构地区 天津市第一中心医院心内科
出处 《国际心血管病杂志》 2013年第6期356-358,共3页 International Journal of Cardiovascular Disease
关键词 肌钙蛋白 自身抗体 心血管疾病
分类号 R54 [医药卫生—心血管疾病]
  • 相关文献

参考文献16

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同被引文献64

  • 1Xu-peiHUANG Jian-fengDU.Troponin I, cardiac diastolic dysfunction and restrictive cardiomyopathy[J].Acta Pharmacologica Sinica,2004,25(12):1569-1575. 被引量：6
  • 2马庆华,张钲,王恒大.髓过氧化物酶与急性冠脉综合征[J].国外医学（心血管疾病分册）,2005,32(1):26-28. 被引量：5
  • 3程翔,廖玉华,李彬,杨亚利,张金盈,逯保军,葛洪霞,刘英,郭张强,张玲.早期美托洛尔治疗对急性心肌梗死大鼠心肌炎症因子表达和心功能的影响[J].中华心血管病杂志,2005,33(5):448-452. 被引量：44
  • 4杜于茜,陈君柱.蛋白质组学及其在心脏研究中的应用进展[J].心血管病学进展,2007,28(5):786-789. 被引量：1
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引证文献3

二级引证文献6

国际心血管病杂志
2013年 第6期

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