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抑郁症的发育起源及机制研究

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摘要 抑郁症是一种以情感低落、快感缺乏、易怒、注意力集中困难、食欲和睡眠异常为主要表现的神经症。除了可能导致自杀倾向外，抑郁症患者还易罹患冠心病和Ⅱ型糖尿病。在全球范围内，抑郁症的发病率有逐年增加的趋势。在欧洲，抑郁症是主要的致残疾病，年患病率约5％；在日本和美国，抑郁症的终身患病率分别达到3％和16．9％；在中国，其患病率3％～5％，给社会和家庭造成了沉重的负担。
作者 程思源 余樱 张崇 汪晖
机构地区 武汉大学基础医学院药理系 武汉大学人民医院神经内科
出处 《医学新知》 CAS 2013年第5期319-323,共5页 New Medicine
基金 国家自然科学基金重点和重大国际合作项目（No.30830112 81220108026）
关键词 抑郁症 胎儿起源 下丘脑-垂体-肾上腺轴 脑源性神经营养因子 表观遗传
分类号 R749.4 [医药卫生—神经病学与精神病学] R714.5 [医药卫生—妇产科学]
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医学新知
2013年 第5期

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