摘要
目的了解医院重症监护病房(ICU)医院感染病原菌分布特征及耐药情况,为临床合理用药提供依据。方法通过回顾性调查,对该医院ICU 2012年度住院病人医院感染病原学标本检测结果进行了调查。结果从该医院ICU全年住院患者感染标本中共分离出病原菌694株,革兰阴性杆菌占86.89%,革兰阳性球菌占13.11%。分离的革兰阴性杆菌中,鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌分居前4位;革兰阳性菌中,主要为金黄色葡萄球菌。革兰阴性杆菌耐药率普遍较高,尤以鲍曼不动杆菌更甚;金黄色葡萄球菌对β-内酰胺类、氨基糖苷类、大环内酯类及喹诺酮类等耐药率较高。结论该医院ICU住院患者医院感染的病原菌主要为革兰阴性杆菌,且耐药严重,调查结果为合理选用抗菌药物提供了可靠依据。
Objective To investigate the distribution of nosocomial infection pathogens and drug resistance status in ICU and to provide scientific basis for clinical rational medication. Methods The detection result of etiology specimens in ICU of the hospital in year 2012 was retrospectively investigated. Results Of the 694 pathogenic strains, 86. 89% were G- bacilli and 13. 11% were G ＋ cocci. The top 4 detected G - bacilli were Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and the top 1 detected G ＋ cocci was Staphylococcus aureus. The G - bacilli showed high drug resistance ratio, especially Acinetobacter baumannii showed high drug resistance ratio to most drugs. Staphylococ- cus aureus had high drug resistance ratio to most drugs of [3 - lactams, Aminoglycosides and Macrolides. Conclusion The main nosocomial infection pathogen is G - bacilli in ICU of this hospital, which has high drug resistance ratio to most of antibiotics. The results of the investigation provide reliable basis for clinical rational medication.
出处
《中国消毒学杂志》
CAS
北大核心
2013年第10期944-946,共3页
Chinese Journal of Disinfection
关键词
重症监护病房
医院感染
病原菌
耐药性
Intensive Care Unit （ ICU）
nosocomial infection
pathogen
drug resistance
