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胰岛素样生长因子-1对动物被毛生长影响的研究进展 被引量:1

Research Progress on the Effect of IGF-1 on Hair Growth of Animals
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摘要 动物被毛生长是一个复杂的过程,受遗传、内分泌、营养及外界条件等各种因素的影响。而胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)是一种具有促进细胞增殖、分化,调节物质代谢等多种生物活性的多肽分子。研究结果发现,IGF-1对被毛/毛发生长的影响不仅局限于自身,同时介导一些细胞因子对被毛生长的调节作用。为阐明IGF-1在被毛/毛发生长方面的重要作用,文章就国内外IGF-1对动物被毛生长影响的研究进展进行综述。 The growth of hair of animals is a very complicated process which is influenced by various factors such as heredity,endocrine,nutrition and external conditions.The insulin-like growth factor-1(IGF-1)is a bioactive peptide which has effect on the proliferation and differentiation of cell, and regulates metabolism.Many researches have also found that the effect of IGF-1 on some cytokines.This paper reviews the progress of IGF-1 in hair/hair growth so as to show the important role of IGF-1 on hair/hair growth.
出处 《中国畜牧兽医》 CAS 北大核心 2013年第10期169-172,共4页 China Animal Husbandry & Veterinary Medicine
基金 国家自然科学基金项目(31172283) 山西农业大学2009年引进人才科研启动项目(XB2009020) 山西省重点学科建设经费:肉牛 肉羊标准化生产体系的建立-子项目-利用转microRNA技术培育彩色转基因细毛羊 山西省科技攻关项目(20080311034)
关键词 动物 被毛 毛发生长 胰岛素样生长因子-1 信号通路 animal hair/hair growth insulin-like growth factor-1 signaling pathway
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