摘要
采用脑醒喷鼻剂治疗急性缺血性中风 2 6例 ,总有效率 96.2 % ,与尼莫通组比较无显著性差异。治疗组的神经功能缺损改善情况优于尼莫通组。同时测定了血液流变学、自由基三项、血栓素B2 、前列环素等项指标。结果显示这些指标治疗前后比较有显著性差异 ;与对照组比较 ,治疗组的全血粘度、LPO、SOD、GSH-Px等也有显著性差异。
A single-blind randomized clinical trial was carried out to observe the effect of Naoxing Nasal Spray on acute ischemic stroke. Thirty-eight cases of acute ischemic stroke were randomly allocated to two groups. The treatment group (26 cases) was treated with Naoxing Nasal Spray and the control group (12 cases) with Nimodipine orally. Hemorheology indexes and serum levels of SOD, GSH-Px, LPO and TXA 2/PGI 2 were measured. The results showed that the total effective rate was 96.2% in the treatment group and 96.1% in the control group (P>0.05), and Naoxing Nasal Spray can improve blood rheology, increase cerebral blood flow, promote the removal of free radical, reduce lipid peroxidation, correct TXA 2/PGI 2 imbalance and counteract thrombus formation.
出处
《中药新药与临床药理》
CAS
CSCD
2000年第6期333-335,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
广东省中医药管理局课题(项目号98342)
关键词
脑醒喷鼻剂/治疗应用
中风/中药疗法
投药
鼻内
Naoxing Nasal Spray/therapeutic use
Stroke/therapy,TCD
Administration,Intrana
