摘要
目的探讨经皮冠状动脉支架植入手术围手术期是否需要预防性使用抗菌药物,以促进抗菌药物的合理使用。方法对医院122例行经皮冠状动脉支架植入术患者临床资料进行回顾性分析,将入选病历按照是否预防使用抗菌药物分为预防组和非预防组,预防组按照Ⅰ类清洁手术预防用药原则预防性给予抗菌药物,非预防组未给予抗菌药物,比较两组总体术后感染率及具有糖尿病、高龄等感染危险因素患者术后感染率是否存在显著差异。结果 122例患者术后除1例因室颤死亡外,共10例出现感染,其中预防组5例,占8.33%;非预防组5例,占8.06%;28例糖尿病患者中,预防组共18例,感染2例,感染率为11.1%;非预防组共10例,感染1例,感染率为10.0%,两组感染率比较差异无统计学意义;入选的61例高龄患者中,预防组28例,感染3例,感染率为10.7%;非预防组共33例,感染4例,感染率为12.1%,两组术后感染率比较差异无统计学意义。结论经皮冠状动脉支架植入手术围手术期不需预防性使用抗菌药物。
OBJECTIVE To determine whether or not the antibiotics prophylaxis should be performed during the perioperative period of coronary stent implantation so as to promote the rational use of antibiotics. METHODS The clinical data of 122 patients who underwent percutaneous coronary stent implantation were retrospectively analyzed, then all the enrolled cases were divided into the prophylaxis group and the non-prophylaxis group according to the prophylactic use of antibiotics~ the prophylaxis group was given the antibiotics based on the principle of antibiotics prophylaxis for type I clean surgery, while the non-prophylaxis group was not given the antibiotics; the total incidence of postoperative infections was compared with that of the patients with such risk factors as diabetes and advanced age. RESULIN Of totally 122 cases （except for 1 case, died of ventricularfibrillation）, the infections occurred in 10 cases, including 5 （8.33%） cases in the prophylaxis group and 5 （8.06%） cases in the non-prophylaxis group. Of totally 28 patients with diabetes, the infections occurred in 2 of 18 cases in the prophylaxis group with the infection rate of 11. 1%, and the infections occurred in 1 of 10 cases in the non- prophylaxis group with the infection rate of 10. 0%, the difference in the infection rate between the two groups was not statistically significant. Of totally 61 cases of advanced patients enrolled, the infection occurred in 3 of 28 cases in the prophylaxis group with the infection rate of 10.7%, and the infections occurred in 4 of 33 cases in the non- prophylaxis group with the infection rate of 12. 1%, tb.e difference in the incidence of postoperative infections between the two groups was not statistically significant. CONCLUSION It is not necessary to use of prophylactic antibiotics during the perioperative period of percutaneous coronary stent implantation.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第21期5280-5282,共3页
Chinese Journal of Nosocomiology
基金
国家自然科学基金资助项目(81273741)
关键词
冠状动脉支架植入
抗菌药物
预防
Coronary stent implantation
Antibiotic
Prophylaxis
