摘要
目的了解医院住院患者抗菌药物使用及细菌学检查情况,为合理使用抗菌药物提供依据。方法采取床旁调查和查阅病历相结合的方法,对2011年10月17日的1857例住院患者抗菌药物使用及细菌学检查情况进行横断面调查。结果 1857例患者中使用抗菌药物706例,抗菌药物使用率为38.02%,其中治疗使用率为60.20%,预防使用率27.90%,治疗加预防使用率11.90%,一联用药使用率79.75%;治疗用药病原体送检率为29.86%,分离出病原菌148株,其中革兰阴性杆菌109株占73.65%,以铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌、鲍氏不动杆菌为主,分别占20.95%、15.54%、14.19%、13.51%;革兰阳性球菌29株占19.59%,真菌10株占6.76%,病原菌主要来源于呼吸道和泌尿道占76.36%。结论Ⅰ类清洁切口手术预防使用抗菌药物比例偏高,应提高标本的送检率,进一步规范抗菌药物的使用。
OBJECTIVE To investigate the use of antimicrobial agents of the hospitalized patients and bacteriological examination so as to provide basis for the rational use of antibiotics. METHODS By means of bedside investigation combined with review of medical records, the cross-sectional survey was conducted for the use of antibiotics and the bacteriological examination of 1857 patients who were hospitalized on Oct 17,2011. RESULTS Of totally 1857 cases of patients, 706 cases used antibiotics with the utilization rate of 38.02%, among which 60.20% used for treatment, 27. 90% for prophylaxis, and 11. 90% for treatment plus prophylaxis; the use rate of one-drug medication was 79.75% ; the rate of submitted pathogens for therapeutic medication was 29.86%. A total of 148 strains of pathogens were isolated, among which there were 109 （73.65%） strains of gram-negative bacilli, 29 （19.59 % ） strains of gram-positive cocci, and 10 （6.76% ） strains of fungi; Pseudornonas aeruginosa （ 20.95%）, Escherichia coli （15.54% ） , Klebsiella pneumoniae （ 14. 19% ） and Acinetobacter baumannii （ 13. 51%） were the predominant species of gram-negative bacilli; 76.36% of the pathogens were isolated from the respiratory tract and the urinary tract. CONCLUSION The proportion of prophylactic use of antibiotics for the type I clean incision surgery is relatively high, it is necessary to improve the submission rate of specimens and further standardize the use of antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第21期5266-5268,共3页
Chinese Journal of Nosocomiology
基金
河北医科大学第二医院基金课题(2010-19)
关键词
抗菌药物
横断面调查
细菌学
合理用药
Antibiotic
Cross-sectional study
Bacteriology
Rational medication
