摘要
目的检测并鉴定浙江嘉兴地区住院患儿感染的呼吸道病毒,以了解该地区呼吸道病毒感染流行趋势,为预防、控制疾病的流行提供依据。方法采用直接免疫荧光法(DFA)对2008年7月-2011年6月住院的8594例出生1d～13岁的呼吸道疾病患儿痰标本中的呼吸道合胞病毒(RSV)、甲型流感病毒(FluA)、乙型流感病毒(FluB)、副流感病毒1、2、3型(PIV-1,2,3)、腺病毒(ADV)、人偏肺病毒(HMPV)共8种病毒进行检测。结果 8594例患儿中病毒检测阳性者2177例,病毒总体阳性率25.33%;检测出的首位病毒为RSV 1143例,占52.50%;3～6岁年龄组病毒检出率最高,达37.52%,毛细支气管炎病毒检出率最高为53.85%。结论病毒在呼吸道感染患儿中占有重要的地位,检出率在3～6岁组段最高,毛细支气管炎患儿感染率最高,以RSV最为常见。
OBJECTIVE To detect and identify the viruses causing respiratory tract infections in hospitalized children in Jiaxing area so as to understand the epidemic trend of respiratory tract infections and provide basis for the prevention and control of diseases. METHODS By means of the direct immunofluorescence assay, totally 8 species of viruses including respiratory syncytial virus （RSV）, influenza A virus （FluA）, influenza B virus （FluB）, parainfluertza virus type 1,2,3 （PTV-1,2,3）, adenovirus （ADV）, and human metapneumovirus （HMPV） were detected in the sputum specimens obtained from 8594 children with respiratory diseases, aged between 1 day and 13 years, who were hospitalized from Jul 2008 to Jul 2011. RESULTS Of totally 8594 cases of patients, there were 2177 cases with the virus tested positive, the total positive rate was 25. 33%. The RSV ranked the first place among the species of viruses detected, which was tested positive in 143 （52.50%） cases; the detection rate of, the viruses was the highest in the patients aged between 3 and 6 years old, reaching up to 37.52%, the detection rate of the viruses was the highest （53.85%） in the patients with capillary bronchitis. CONCLUSION The viruses are the main pathogens causing respiratory tract infections in the children, the detection rate of the viruses is the highest in the children aged between 3 and 6 years, and the incidence rate of viral infections is the highest in the children with capillary bronchitis; the RSV is the predominant species.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第21期5239-5240,5243,共3页
Chinese Journal of Nosocomiology
基金
中国医学科学院青年基金资助项目(9331014)
关键词
呼吸道病毒感染
直接免疫荧光
呼吸道病毒
Respiratory tract with viral infection
Direct immunofluorescence assay
Respiratory tract virus
