摘要
目的验证改良法磁共振评分系统对其他检查方法诊断为阴性或不能定性诊断的乳腺占位性病变的诊断价值。方法选取2011年12月。2012年10月青海省人民医院临床或其它检查方法诊断为阴性或不能定性诊断的非典型性乳腺疾病患者57例，均行X线钼靶检查、超声及磁共振检查，比较三者的诊断率。并用受试者工作特性曲线（ROC）计算表面扩散系数（ADC）及改良法磁共振评分的诊断敏感性和特异性。结果X线与超声对病变的诊断率分别为59．6％和68．9％，改良法磁共振评分为91．2％．差异有高度统计学意义（P〈0．01）。ADC值及改良磁共振评分ROC面积为72．2％和81．3％，以ADC值为1．19×10^-3mm2／s诊断阈值时，其诊断敏感度为84．1％，特异度为89．8％，以改良法磁共振评分5．5分作为诊断阈值时，其诊断敏感度、特异度为94．1％和88．3％，差异有高度统计学意义（P〈0．01）。结论磁共振乳腺成像能够更早的发现微小病灶，而改良法评分系统的应用大大的提高了诊断的敏感性和特异性，具有十分重要的临床意义。
Objective To evaluate the diagnostic value of reformed MRI points-scoring system to atypical breast benign and malignant lesions. Methods 57 patients with negative diagnosis by clinical or other method and non-qualitative diagnosis of atypical breast disease from December 2011 to October 2012 in Qinghai Provincial People＇s Hospital were collected, all the patients were examined by X-ray mammography check, ultrasound, MRI; the diagnostic rate was compared. The sensitivity and specificity of ADC and reformed MRI points-scoring system were calculated by the ROC. Results The diagnostic rate of Mammography, ultrasound were 59.6% and 68.9% respectively. The diagnostic rate of reformed MRI points-scoring system was 91.2%, the difference was statistically significant （P 〈 0.01）. The area under ROC of ADC and reformed MRI pointsscoring system were 72.2% and 81.3%. The diagnostic sensitivity and specificity were 84.1% and 89.8% respectively with the ADC threshold value of 1.19×10^-3 mm^2/s. The diagnostic sensitivity and specificity were 94.1% and 88.3% respectively with the reformed MRI points-scoring system threshold value of 5.5 points, the difference was statistically significant （P 〈 0.01）. Conclusion MRI can discover the focus in the early time. Reformed MRI points-scoring system can improve the sensitivity and specificity, this is very helpful for clinic.
出处
《中国医药导报》
CAS
2013年第31期64-66,70,共4页
China Medical Herald
关键词
非典型乳腺疾病
改良法磁共振评分
诊断价值
Atypical breast diseases
Reformed MRI points-scoring system
Diagnostic value
