摘要
目的:观察暖宫贴配合甲硝唑、地塞米松治疗慢性盆腔炎的临床疗效和对免疫功能的影响,为临床的治疗提供参考。方法:选取我院妇科门诊就诊的220例慢性盆腔炎患者,随机将其分为观察组和对照组各110例。观察组采用暖宫贴配合甲硝唑、地塞米松灌肠治疗,对照组则采用微波治疗配合甲硝唑、地塞米松灌肠治疗。对比两组患者的临床疗效和免疫功能的变化情况。结果:经过治疗后,观察组痊愈率为54.44%(60/110),总有效率为90.00%(99/110);对照组痊愈率为38.18%(42/110),总有效率为74.55%(82/110)。观察组的痊愈率和总有效率明显优于对照组。观察组经过治疗后,其CD4、CD4/CD8均较治疗前明显升高,而对照组治疗前后的CD4以及CD4/CD8对比,差异没有统计学意义;两组患者治疗前后的CD8水平均有明显的下降。两组患者治疗后的CD4、CD8以及CD4/CD8的组间对比,其差异有统计学意义。观察组患者治疗过程中,没有出现明显的不良反应。对照组有9例患者在第一次灌肠后出现轻度腹泻。结论:暖宫贴配合甲硝唑、地塞米松治疗慢性盆腔炎具有较好的临床疗效,且操作较为简便,安全性高,值得在临床上进一步推广应用。
Objectives： To observe the clinical effect of warm uterus paste with metronidazole, dexamethasone in the treat- ment of chronic pelvic inflammatory disease and its influence on immune function, and to provide the reference for the chnical treatment. Method： 220 patients with chronic pelvic inflammatory disease in the gynecology clinic of our hospital were selected, and randomly divided into the observation group and the control group. The observation group were treated with warm uterus paste, dexamethasone plus metronidazole enema, while the control group were treated with microwave therapy with metronidazole enema and dexamethasone. The changes in clinical efficacy and immune function were compared between both groups. Results： After treatment, the cure rate of observation group was 54. 44% （60/110）, the total effective rate 90% （99/110） ; in the control group, the cure rate is 38.18% （42/110）, the total effective rate 74. 55% （82/110）. The cure rate and total effective rate of the observation group were high than those of the control group. In the observation group, CIM, CIM/CD8 were significantly in- creased after treatment, while in the control group the differences of CIM and CIM/CD8 before and after treatment were not statis- tically significant; before and after treatment, the CD8 levels decreased significantly in both groups. The patients in the observa- tion group showed no significant adverse reactions. In the control group, nine patients had mild diarrhea in the first enema. Con- dusion： Warm uterus paste with metronidazole, dexamethasone therapy has good clinical effect in treating chronic pelvic inflam- matory disease. The operation is simple, safe, is worth popularizing in clinic.
出处
《中国性科学》
2013年第10期71-74,共4页
Chinese Journal of Human Sexuality
关键词
暖宫贴
甲硝唑
地塞米松
慢性盆腔炎
Warm uterus paste
Metronidazole
Dexamethasone
Chronic pelvic inflammation
