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磁共振成像及磁共振波谱成像诊断前列腺癌的价值 被引量:4

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摘要 目的:分析3.0 T磁共振成像(3.0 TMRI)及磁共振波谱成像(MRS)两种成像方法及其联合应用对前列腺癌的诊断价值。方法:收集经病理或临床证实的28例前列腺癌(PCa)及20例前列腺增生(BPH)患者资料,两组患者行MRI及MRS,MRS观察病灶枸橼酸盐(Cit)、胆碱(Cho)和肌酸(Cre)的波峰,测量(Cho+Cre)/Cit(CC/C)比值,通过受试者操作特性曲线(ROC)评估CC/C比值对PCa的诊断效能,观察MRI单独应用及与MRS联用的差异。结果:PCa的CC/C平均值为3.04±0.360,BPH的CC/C平均值为0.515±0.072(P﹤0.05);ROC曲线评估显示CC/C比值诊断PCa的最佳诊断域值为1.110,此诊断域值的敏感度92.9%和特异度93.7%,MRS与MRI联用的敏感度96.42%,特异度90.00%。结论:3.0 TMRI和MRS联合应用有助于前列腺癌的早期诊断与鉴别诊断。
出处 《贵阳医学院学报》 CAS 2013年第5期527-530,共4页 Journal of Guiyang Medical College
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