摘要
目的探讨经颅多普勒超声监测脑血流动力学参数对早期发现多发性脑梗塞患者认知障碍的应用价值。方法对156例维吾尔族多发性脑梗塞(MI)患者进行经颅多普勒超声(TCD)、简易智力状况检查量表(MMSE)动态监测,每3个月监测1次,共24个月,对结果进行统计分析。结果多发性脑梗塞性痴呆(MID)发病率为25.0%(39/156),其中23例发生于随访的9个月后,占58.9%;随访中出现痴呆的患者的平均血流速度(Vm)降低,而搏动指数(PI)增加。与单纯MI组相比,两组Vm从9个月开始即显示出明显的差异,较MID的发生高峰提前约3个月。结论用TCD动态监测维吾尔族MI患者的脑血流动力学参数对早期发现多发性脑梗塞患者认知障碍有重要价值。
Objective To evaluate the value of transcranial Dopper（TCD）in screening multiple cerebral in-farction patients with cognitive impairment.Methods 1 5 6 Uygur Patients with MI were determined regu-larly every 3 months with TCD and MMSE for 24 months.Results Among 156 patients with MI,the inci-dence of multiple infarct dementia（MID）was 25.0%（39/156）,23 cases occurred during the period of 9 months,accounting for 58.9%（23/39）;Among patients with and without dementia,significant difference was found in Vm and PI.Compared with the simple MI group,significant Vm appeared in the 9th month. Conclusion It is valuable to determine Vm and RI regularly for early diagnosis of cognitive impairment of patients with muti-infarction.
出处
《新疆医科大学学报》
CAS
2013年第10期1467-1469,共3页
Journal of Xinjiang Medical University
基金
国家自然科学基金(81160145)
关键词
经颅多普勒超声
动态监测
认知障碍
早期诊断
transcrannial Dopper
dynamic determine
cognitive impairment early diagnosis
