摘要
目的：探讨分析在超声引导下采用未成熟卵泡抽吸术（IMFA）的治疗方法对多囊卵巢综合征（PCOS）合并不孕的患者卵巢窦卵泡计数和内分泌功能的影响。方法：选择2008年3月-2011年3月该院生殖医学中心收治的46例PCOS不孕患者，超声引导下对所有患者行IMFA，对比观察IMFA治疗前后患者卵巢窦卵泡计数和内分泌功能的变化，同时观察卵巢排卵功能的恢复情况及妊娠情况。结果：46例PCOS不孕患者经过2～3个周期的IMFA治疗后，患者睾酮（T）水平明显降低、黄体生成素（LH）和卵泡刺激素（FSH）比值也显著降低，与治疗前对比，差异具有统计学意义（P〈0．05）。术后有37例患者卵巢窦卵泡计数降低至10个以下；术后对患者连续随访半年，共有22例患者成功妊娠。结论：IMFA能显著降低PCOS不孕患者的卵巢窦卵泡计数，并且能显著改善内分泌状况，可以作为PCOS不孕患者一种有效可行的治疗方法。
Objective：To explore the effect of ultrasound -guided immature follicular aspiration （IMFA） on ovarian antral follicular count and endocrine function of infertile patients with polycystic ovary syndrome （PCOS）. Methods：Forty- six infertile patients with PCOS treated in center of reproductive medicine in the hospital from March 2008 to March 2011 were selected, ultrasound - guided IMFA was con- ducted, the changes of ovarian antral follicular count and endocrine function before and after IMFA were compared and observed ; the recover- y of ovarian oviposit function and pregnancy condition were observed simultaneously. Results： After IMFA for 2 - 3 courses of treatment, the level of testosterone in 46 infertile patients with PCOS decreased significantly, the ratio of luteinizing hormone （LH）/follicle -stimulating hormone （FSH） also decreased significantly, compared with those before IMFA, there were statistically significant differences （ P 〈 0. 05 ）. After IMFA, ovarian antral follicular count of 37 patients decreased to less than 10; the patients were continuously followed up for half a year after IMFA, a total of 22 patients got pregnancy successfully. Conclusion：IMFA can significantly reduce ovarian antral follicular count of in- fertile patients with PCOS and markedly improve endocrine condition, which can be used as an effective therapeutic method.
出处
《中国妇幼保健》
CAS
北大核心
2013年第32期5322-5324,共3页
Maternal and Child Health Care of China
基金
江苏省盐城市科技发展计划项目〔YK2007136〕
关键词
未成熟卵泡抽吸术
多囊卵巢综合征
不孕
超声引导
Immature follicular aspiration
Polycystic ovary syndrome
Infertility
Ultrasound - guided
