摘要
A recently identified phenylpropanoid isolated from Peperomia tetraphylla was synthesized in enantiopure forms using an aldol condensation of enantiopure （R）-N-acetyl 4-phenyl-oxazolidin-2-one as the key step. With the aid of the single crystal X-ray crystallographic analysis of the synthetic sample, the configuration for the natural product was unambiguously established. Corrected/updated ^13C NMR and optical rotation are also presented.
A recently identified phenylpropanoid isolated from Peperomia tetraphylla was synthesized in enantiopure forms using an aldol condensation of enantiopure （R）-N-acetyl 4-phenyl-oxazolidin-2-one as the key step. With the aid of the single crystal X-ray crystallographic analysis of the synthetic sample, the configuration for the natural product was unambiguously established. Corrected/updated ^13C NMR and optical rotation are also presented.
基金
Acknowledgement This work was supported by the National Basic Research Program of China （the 973 Program, No. 2010CB833200）, the National Natural Science Foundation of China （Nos. 21172247, 21032002, 20921091） and the Chinese Academy of Sciences.
