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乌司他丁治疗胶原诱导关节炎的实验研究 被引量：3

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摘要 类风湿关节炎（rheumatoid arthritis,RA）是一种以慢性关节炎症和骨质破坏为主要特征的全身性自身免疫性疾病,如不经正规治疗,可出现关节畸形,严重影响患者的生活质量.RA的基本病理特征是滑膜炎伴关节软骨和骨质的破坏,炎症细胞浸润、滑膜细胞过度增殖以及破骨细胞活化均参与RA的病理过程.其中T淋巴细胞活化及炎性细胞因子表达增加在RA的发生和发展过程中起了非常重要的作用.
作者 孙琳 李常虹 郑晓娟 赵金霞 刘蕊 刘湘源
机构地区 北京大学第三医院风湿免疫科
出处 《北京大学学报（医学版）》 CAS CSCD 北大核心 2013年第5期823-826,共4页 Journal of Peking University:Health Sciences
基金 国家自然科学基金(81072474) 北京市自然科学基金(7112143) 广东天普研究基金(01201007)资助~~
关键词 关节炎 类风湿 乌司他丁 胶原Ⅱ型
分类号 R593.22 [医药卫生—内科学]
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参考文献21

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  • 5曾文红,白国强.乌司他丁研究进展[J].中华肝胆外科杂志,2001,7(1):52-54. 被引量：143
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二级参考文献18

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北京大学学报（医学版）
2013年 第5期

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