摘要
目的 评价侵袭性牙周炎（aggressive periodontitis,AgP）核心家系中先证者和父母的牙槽骨吸收状况、冠根比和牙根形态异常,探讨牙根形态异常和剩余牙槽骨的关系及牙根形态的遗传度.方法 19个AgP核心家系,先证者19例（男性9例,女性10例）,平均年龄23.6岁,父母38人（父亲19人,母亲19人）,平均年龄51.0岁.根据全口根尖片测量剩余牙槽骨占根长的百分比,评价牙根形态异常牙数,测量冠高、根长和冠根比,分别计算牙根形态异常、冠根比和前磨牙锥形根的遗传度.结果 先证者及父母全口牙齿平均剩余牙槽骨百分比分别为（58.9±4.3）％和（62.3±3.7）％；牙根形态异常牙的剩余牙槽骨骨量为（67.5±22.2）％,非牙根形态异常牙剩余牙槽骨百分比为（73.1±18.7）％,两者差异有统计学意义（P＜0.001）；牙根形态异常、冠根比和前磨牙锥形根在核心家系中的遗传度分别为30.3％、46.8％和40.1％.结论 核心家系成员中牙根形态异常牙剩余牙槽骨量少于非牙根形态异常牙；牙根形态异常、冠根比和双尖牙锥形根有遗传倾向,是遗传因素和环境因素共同作用的结果.
Objective To evaluate the status of residual alveolar bone in aggressive periodontitis （AgP） nuclear families and to investigate the influence of teeth with root abnormity on residual alveolar bone and the heredity of root abnormity,the premolar cone-root and proportion of crown and root.Methods Nineteen AgP probands（9 males and 10 females） at average age of 24.5 and 38 parents at average age 51.0 were included.A full set of periapical radiographs of all the subjects were taken.The residual alveolar bone of each tooth was measured by the ratio（shown as percentage） of the distance between apical and the alveolar bone crest to the whole root length.The abnormity of roots was detected on a full set of periapical radiographs.All the roots and crowns of teeth were measured.The relationship between the residual bone and the ratio was studied.The heredity grade of the premolar cone-root,proportion of crown and root,and root abnormity were computed.Results The average residual alveolar bone of probands was less than that of their parents.In 11 families,the father＇ s residual alveolar bone was less than that of the mother＇ s.The average residual alveolar bone of the teeth with root abnormity was less than that of normal teeth.The average residual alveolar bone of the teeth with abnormity of roots and the normal teeth were （67.5 ± 22.2） % and （73.1 ± 18.7） % respectively,with statistical significance （P 〈 0.001）.The heredity grade of the premolar cone-root was 40.1%,the heredity grade of proportion of crown and root was 46.8%,the heredity grade of root abnormity was 30.3%.Conclusions The residual alveolar bone of the teeth with root abnormity was less than that of normal teeth in nuclear families.The heritability of the root abnormity,the cone-root and proportion of crown and root in our sample was 0.3-0.5,which means that genetic factors accounted for about one third to half of the efficiency for AgP.
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2013年第10期577-580,共4页
Chinese Journal of Stomatology
基金
国家自然科学基金（30973319、81100748）
“十一五”国家科技支撑计划（2007BAIl8802）
首都医学发展科研基金（20092033）
关键词
侵袭性牙周炎
牙槽骨吸收
牙根
遗传度
Aggressive periodontitis
Alveolar bone lose
Tooth root
Heredity grade
