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甲状腺疾病患者β_2微球蛋白水平与甲状腺激素水平的相关性研究 被引量:7

A relative analysis between serum β_2-microglobulin and thyroid hormone in thyroid diseases
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摘要 目的探讨甲状腺疾病患者血清β2微球蛋白(β2-M)水平与甲状腺激素水平的相关性。方法选择80例甲状腺疾病患者,按甲状腺激素(T3和T4)水平分为升高组、正常组和降低组3组,与健康体检者80例作对照组,用放射免疫法(RIA)检测各组β2-M水平,并进行统计学分析。结果 T3、T4升高组血清β2-M水平明显高于对照组(P<0.05),T3、T4正常组和降低组与对照组比较差异无统计学意义(P>0.05)。结论甲状腺疾病患者血清β2-M水平与甲状腺激素水平有密切关系,提示β2-M可作为评价甲亢患者疗效观察和病情判断的重要辅助指标之一。 Objective To investigate the correlation between β2-microglobulin (β2-M)and thyroid hormone in thyroid diseases.Methods The levels of serum β2-M were detected for 80 patients with thyroid diseases and 80 health people by RIA.Patients were divided into three group:increasing group of T3 and T4,reducing group of T3 and T4 and normal group of T3 and T4.Results Serum β2-M level of the increasing groups of T3 and T4 was significantly higher than that in control group (P&lt;0.05).There was no differences between non-increasing groups of T3 and T4 and control group(P&gt;0.05).Conclusion β2-microglobulin and thyroid hormone was closely related in thyroid diseases.Serum β2-microglobulin was useful to judge the the therapeutic effects of thyroid diseases.
作者 乔维洲 宋晶
出处 《国际检验医学杂志》 CAS 2013年第20期2684-2685,共2页 International Journal of Laboratory Medicine
关键词 甲状腺疾病 Β2微球蛋白 甲状腺激素 thyroid diseases β2-microglobulin thyroid hormone
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