摘要
目的探讨化痰解郁法治疗帕金森病伴轻中度抑郁的有效性及安全性。方法将70例帕金森病伴轻中度抑郁患者随机分为观察组35例,对照组35例。对照组给予西医治疗,观察组给与化痰解郁法组方汤剂。观察两组患者治疗前及治疗后帕金森评定量表、汉密尔顿抑郁量表、临床总体印象-疾病严重程度量表评分及两组的不良反应。结果观察组在汉密尔顿抑郁量表、严重程度量表评分与对照组比较差异有统计学意义(P<0.05),且不良反应较少。结论化痰解郁法治疗帕金森病伴轻中度抑郁能明显减轻汉密尔顿抑郁量表、严重程度量表评评分,促进康复,且耐受性高。
Objective To observe the efficacy and safety of treating the Parkinson ＂s disease （ GanYuTanYun Type） with mild-to-moderate depression. Methods 70 patients with Parkinson＇s disease with mild-to-moderate depression were randomly divided into observation group and control group, 35 cases of control group 35 cases; The control group gives the western medicine treatment, the observation group to HuaTanGieYu method. Observe two groups before and af- ter treatment in patients with Parkinson＇s disease rating scale （ UPDRS） and Hamilton depression scale （HAMD - 17） overall impression - the severity of disease, clinical scale （ CGI -s） score and two groups of adverse reactions. Results Observation group in the HAMD, CG1 -s score difference was statistically significant compared with controls （p 〈 0.05）, and less adverse reaction. Conclusion HuaTanGieYu treatments for Parkinson＇s disease with mild-to-moderate depres- sion can significantly reduce the HAMD, CGI - S score, promote rehabilitation, and durability.
出处
《菏泽医学专科学校学报》
2013年第3期24-26,共3页
Journal of Heze Medical College
