摘要
目的:观察急性心肌梗死伴发肾动脉粥样硬化性狭窄(atherosclerotic renal artery stenosis,ARAS)≥70%患者的远期预后。方法:收集205例急性心肌梗死患者临床资料,患者同时进行了冠状动脉和肾动脉血管造影检查,随访主要心脑血管不良事件:死亡、脑卒中、心力衰竭、非致死性心肌梗死及冠脉血运重建。复合终点事件是指任何上述不良事件。结果:随访期间共有31例(15.1%)出现心力衰竭,其中ARAS患者10例(25.6%),非ARAS患者21例,二者差异有统计学意义(P=0.049);ARAS患者中有22例(56.4%)出现复合终点事件,非ARAS患者中有38例(22.9%)出现复合终点事件,二者差异有统计学意义(P=0.000);多因素Cox回归分析显示,ARAS是急性心肌梗死后发生心力衰竭的预测因素。结论:ARAS与发生心力衰竭相关,并与远期发生主要心脑血管不良事件的复合终点相关。
Objective：To observe the effect of atherosclerotic artery renal artery stenosis （ARAS） ≥70% on long-term prognosis in patients with acute myocardial infarction （AMI）. Methods： All 205 cases with AMI had underwent coronary and renal artery angiography. The main cardiovascular and cerebrovascular adverse events including death, stroke, heart failure, nonJfatal myocardial infarction and revascularization were monitored during follow-up. Composite endpoints were defined as occurrence of the above adverse events. Results： Thirty-one patients （15.1%） suffering heart failure. Heart failure occurred in 10 patients （25.6%） with ARAS, while in 21 patients （12.7%） without-ARAS （P=0. 049）. Composite events occurred in 22 patients （56.4%） with ARAS, while in 38 patients （22.9%） without-ARAS, there was a significant difference between the two groups （P= 0. 000）. Cox regression analysis showed that only ARAS predicted heart failure in paients with AMI. Conclusion： ARAS is related to the occurrence of heart failure and the composite endpoint of long-term adverse events.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2013年第10期738-741,共4页
Journal of Clinical Cardiology
关键词
急性心肌梗死
粥样硬化性肾动脉狭窄
心力衰竭
预后
acute myocardial infarction
atherosclerotic renal artery stenosis ARAS
heart failure
prognosis
