摘要
目的探讨益气养阴、活血化瘀法防治糖尿病视网膜病变的临床效果。方法选择2型糖尿病符合糖尿病视网膜病变(DR)高风险条件证属中医气阴两虚、血瘀络阻的患者,共100例(200眼),按1∶1比例随机分为治疗组和对照组,治疗组给予益气养阴、活血化瘀中药干预,对照组无中药干预(两组观察期间均以综合疗法控制血糖),观察1年后分析DR发生情况。结果除失访者12例和因视网膜脱离激光治疗1例外,实际纳入病例87例(174眼),其中治疗组42例(84眼),对照组45例(90眼),最终发生DR者治疗组16只眼(占19.0%);对照组38只眼(占42.2%),两组DR的发生率比较差异有统计学意义(c2=10.902,P=0.001),治疗组明显低于对照组。结论以益气养阴、活血化瘀法干预治疗DR高风险患者证属气阴两虚、血瘀络阻证者,可在一定程度上阻止或延缓DM向DR的进展。
OBJECTIVE To study the effect of Yiqi Yangyin and Huoxue Huayu method for the high-risk diabetic retinopathy（DR） patients. METHODS One hundred cases （200 eyes） of high-risk DR patients who were diagnosed with qi and yin deficiency were randomly divided into treatment group and control group. Treatment group was treated by Yiqi Yangyin and Huoxue Huayu medicine, and control group was blank control（two groups applied comprehensive therapy to control blood sugar）. One year later, we analyzed the happening cases of DR. RESULTS Except twelve lost cases and one case with the laser treatment because of retinal detachment, eventually 87 cases （174 eyes） Included. There were 42 cases （84 eyes） in the treatment group and 45 cases （90 eyes） in control group. The total occurrence of treatment group was 16 eyes （19.0%）; the total occurrence of control group was 38 eyes （42.2 % ）. Compared the two groups, the difference was statistically significant （χ^2= 10.902, P =0.001 〈 0.05 ）. The occurrence of the treatment group was significantly lower than that of the control group. CONCLUSIONS Yiqi Yangyin and Huoxue Huayu method was effective and safe. In a certain extent, it could prevent or delay the progress of DM to DR.
出处
《中国中医眼科杂志》
2013年第5期324-327,共4页
China Journal of Chinese Ophthalmology
基金
中国中医科学院广安门医院基金课题(2008S)
