摘要
目的:探讨福辛普利联合阿托伐他汀钙治疗原发性高血压伴高血脂的临床疗效和安全性。方法:将80例原发性高血压伴高血脂患者随机分为观察组和对照组(各40例),观察组给予福辛普利联合阿托伐他汀钙治疗,对照组给予厄贝沙坦联合阿托伐他汀钙治疗,治疗6个月后,观察比较两组患者血压、血脂水平和肾功能等各项指标。结果:治疗6个月后两组患者血脂水平均有明显改善,与治疗前比较,差异有统计学意义(P<0.01)但组间比较差异无统计学意义(P>0.05)。观察组患者血压和肾功能指标好于对照组,差异有统计学意义(P<0.05)。结论:福辛普利联合阿托伐他汀钙治疗原发性高血压伴高血脂,可以使患者血压持续稳定在较低水平,能改善血脂各项指标和保护肾功能。
objective: to study the Fosinopril atorvastatin calcium in treatment of primary hypertension complicated with hyperlipemia: clinical efficacy and safety.Method of 80 cases of primary hypertension complicated with hyperlipemia patients randomly assigned to observer group and the control group(40 cases),observer groups giving Fosinopril atorvastatin calcium in treatment,against granting of irbesartan combined with atorvastatin calcium in treatment,treatment for 6 months after,observation and comparison of two groups of patients with various indica tors such as blood pressure,blood lipid and renal function.Result after 6 months ' treatment with two sets of blood lipid levels in patients with significantly improved,compared with before treatment,differences are statistically significant(P0.01)but between the groups is quite the difference was not statistically significant(P0.05).Observer Group on blood pressure and renal function in patients with indicators are better than the control group,the difference statistically significant(P0.05).Conclusions of Fosinopril atorvastatin calcium in the treatment of primary hypertension complicated with hyperlipemia,can allow the patients ' blood pressure continues to be stable at a relatively low level,indicators can improve blood lipid and protection of renal function.
出处
《内蒙古中医药》
2013年第5期1-2,共2页
Inner Mongolia Journal of Traditional Chinese Medicine