摘要
目的研究进口和国产阿莫西林胶囊治疗呼吸道感染的代谢特征及不良反应。方法选择呼吸道感染患者,分为给予进口阿莫西林胶囊口服的对照组和国产阿莫西林胶囊口服的观察组,检测不同时间点的血药浓度、分析药物代谢特征,并观察服药期间的不良反应情况。结果两组患者药物浓度峰值、达到峰值的时间、药物半衰期以及发生不良反应的例数差异无统计学意义。结论进口和国产阿莫西林胶囊治疗呼吸道感染时的代谢特征及不良反应发生情况相当,国产阿莫西林胶囊更适合在基层医院使用。
Objective To study the metabolic characteristics and adverse reaction of domestic and imported amoxieillin capsules in treating respiratory tract infections. Methods Patients with respiratory tract infection were enrolled and divided into observation group given domestic amoxicillin capsules and control group given import Amoxieillin Capsules. Then metabolism characteristic and adverse reaction were observed. Results There were no significant difference in Cmax, Tmax, T＋ and cases of adverse reaction of two group. Conclusion Meta- bolic characteristics and adverse reaction of domestic amoxicillin capsules are equal to imported Amoxicillin Capsules and domestic amoxicillin capsules are suitable for primary hospital.
出处
《继续医学教育》
2013年第8期6-8,共3页
Continuing Medical Education
关键词
呼吸道感染
阿莫西林
代谢特征
药代动力学
Respiratory tract infection
Amoxicillin
Metabolic characteristics
Pharmacokinetic
