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Chiari Ⅰ畸形的发病机制及诊疗进展

Pathogenesis and treatment of Chiari Ⅰ malformation
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摘要 ChiariⅠ畸形是后脑发育异常的先大性畸形,有关其发病机制有很多学说,如容积学说、遗传学说等.而近几年学者们又根据Chiari Ⅰ畸形伴发脊髓空洞症总结了一些新的学说,但具体机制至今未明确.本文从Chiari Ⅰ畸形的定义、发病机制、临床表现、诊断及治疗等角度对该疾病进行综述. Chiari Ⅰ malformation is a congenital anomaly of posterior brain.There has been many theories for its pathogenesis.Recent years,researchers have sunmarized new theories about the pathogenesis of syringomyelia associated Chiari Ⅰ malformation.However,the exact pathogenesis of Chiari Ⅰ malformation has not been clarified.There are a lot of surgical treatments of Chiari Ⅰ malformation.Importantly,there remains no consensus about the best and generally applicable treatment.
出处 《国际外科学杂志》 2013年第9期618-621,共4页 International Journal of Surgery
关键词 CHIARI Ⅰ畸形 容积学说 遗传学说 脊髓空洞症 神经外科(学) 诊断 Chiari Ⅰ malformation Posterior fossa volume Genetics Syringomyelia Neurosurgery Diagnosis
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