摘要
对药食同源植物苦瓜 (MomordicacharantiaL .)的鲜汁冻干粉对动物的降血糖作用及急性毒性进行了药理实验 ,苦瓜冻干粉 (生药量 2 0 g/kg和 40g/kg)对药物性高血糖小鼠具有显著的降血糖作用 ,同时对正常小鼠血糖没有影响 ;苦瓜冻干粉的小鼠口服LD50 为生药量 70 4.8g/kg (95 %可信限生药量 6 18.4～ 80 4g/kg) ,其产生降糖药效的剂量仅为其LD50 的 1/ 35～ 1/ 17。
The pharmacological experiments of freeze\|dried powder of balsam pear (\%Momordica charantia \%L.) fresh fruit juice are carried out. The results showed that the freeze\|dried powder of balsam pear (FDPBP) (crude drugs 20 g/kg and 40 g/kg) has remarkable effect on lowering blood glucose level to mice with pharmaceutical high blood glucose, but no influence to normal mice. LD\-\{50\}took orally in mice of FDPBP is curde drugs 704.8 g/kg (95% limit of believe: crude drugs 618.4～804 g/kg), the effective doses lowering the blood glucose level only are 1/35～1/17 to its LD\-\{50\}.
出处
《植物资源与环境学报》
CAS
CSCD
2000年第3期19-21,共3页
Journal of Plant Resources and Environment
基金
江苏省科学技术委员会社会发展项目!(BS960 2 2 )
关键词
苦瓜
冻干粉
急性毒性
降血糖作用
Momordica charantia \%L.
freeze\|dried powder
balsam pear
acute toxicity
lowering the blood glucose
