摘要
目的研究盐酸罗哌卡因肌注于膝关节周围组织对于人工全膝关节置换(TKA)术后镇痛的临床效果。方法 76例膝关节骨关节炎行TKA术后随机分为2组:注射组(A组),非注射组(B组)。A组缝合切口前给予0.375%盐酸罗哌卡因肌注,B组不注射盐酸罗哌卡因。观察患者术后第1、3、7、14天的疼痛视觉模拟评分(VAS评分)。结果术后第1天平均VAS评分A组4.50分,B组6.86分,差异有统计学意义(P<0.05);术后第3天VAS评分A组4.52分,B组6.07分,差异有统计学意义(P<0.05);术后第7天VAS评分A组3.84分,B组4.39分,差异有统计学意义(P<0.05);术后第14天平均VAS评分A组3.81分,B组3.84分,差异无统计学意义(P>0.05)。术后第1、3、7天A组术后疼痛明显轻于B组。结论盐酸罗哌卡因局部注射对于人工全膝关节置换术后患者早期疼痛的减轻及术后行早期功能锻炼有积极作用。
Objective To investigate the analgesia effect of ropivacaine hydrochioride local injection in patients after total knee arthroplasty. Methods A total of 76 patients with knee osteoarthritis were randomly assigned into 2 groups, injection group （group A）, non injection group （group B）. At the end of operation, 0.375% ropivacaine was injected into muscles and proximal and subcutaneous tissue before incision suture in group A, while group B had no injection of ropivacaine, with conventional suture. On the postoperative first day, third day, seventh day, fourteenth day, VAS score was observed. Results The visual analogue scale （VAS） was used to score knee joint pain. On first day, the score was 4.50 in group A, 6.86 in group B, there＇s significant difference （P 〈0.05）; On third day, 4.52 in group A, 6.07 in group B, there＇s significant difference （P 〈 0.05）; On seventh day; 3.84 in group A, 4.39 in group B, there＇s significant difference （P 〈0.05）; On fourteenth day, 3.81 in group A, 3.84 in group B, there＇s no significant difference （P 〉0.05）. Pain of knee on the first, third, seventh days in group A was significantly milder than group B. Conclusion Ropivacaine hydrochioride local injection plays a positive role in total knee arthroplasty in patients with early postoperative pain relief and early functional exercise.
出处
《中国骨与关节损伤杂志》
2013年第10期926-928,共3页
Chinese Journal of Bone and Joint Injury
基金
长海医院"1255"学科建设计划(CH125530500)
关键词
人工全膝关节置换术
术后疼痛
盐酸罗哌卡因
超前镇痛
Total knee arthroplasty
Postoperative pain
Ropivacaine hydrochioride
Preemptive analgesia
