摘要
肺癌已经成为全球范围内癌症死亡的首位死因,其5年生存率很低。肺癌的筛查和早期诊断是改善肺癌生存,降低肺癌死亡率的关键。低剂量螺旋CT是近20年肺癌筛查的热点,随机对照试验研究已经证实其可降低肺癌死亡率。但目前低剂量螺旋CT筛查仍存在一些问题。本文对近年来低剂量螺旋CT能否降低肺癌死亡率的争议、随机对照试验的结果及存在的问题进行综述,并对未来低剂量螺旋CT在肺癌筛查中的应用做一展望。
Lung cancer has become the leading cause of cancer mortality globally, and 5-year survival rate is very poor. Screening and early detection are vital to improve survival and decrease mortality of lung cancer. In recent 20 years, low-dose spiral CT （LDCT） screening has become a research focus in this area. Randomized controlled trials have conifrmed that LDCT can decrease lung cancer mortality. However, there are still some problems of LDCT. In this paper, we summarized the controversy that whether low-dose helical CT screening can reduce lung cancer mortality or not before its effectiveness was been conifrmed, the results and problems in the randomized controlled trials and gave a prospect of low-dose helical CT screening’s future application.
出处
《中国肺癌杂志》
CAS
北大核心
2013年第10期553-558,共6页
Chinese Journal of Lung Cancer
基金
北京协和青年基金(No.2012X07)资助~~
关键词
低剂量螺旋CT
肺肿瘤
筛查
Low-dose spiral CT
Lung neoplasms
Screening
