摘要
目的探讨pT1期肾透明细胞癌(CCRCC)的CEUS增强模式、定量参数与Fuhrman分级的关系。方法回顾性分析经病理证实的83例pT1期CCRCC的CEUS图像及相关参数,观察不同分级肿瘤的CEUS增强模式、程度及增强的均匀性以及肿瘤周边环状高增强(PHR);通过时间-强度曲线软件得到定量数值,包括始增时间(AT)、达峰时间(TTP)和峰值强度(PI),并与病理Fuhrman分级进行比较。结果不同Fuhrman分级的CCRCC的PHR、△PI值差异均有统计学意义(P均<0.05)。FuhrmanⅠ级肿瘤中PHR检出率相对较高,△PI最低;Ⅳ级肿瘤PHR检出率相对较低,△PI最高。各级肿瘤增强均匀性差异无统计学意义(P>0.05)。肿瘤CEUS增强模式大多表现为"快进"(61/83,73.49%)、"快出"(34/83,40.96%)和"慢出"(37/83,44.58%),不同分级肿瘤造影模式差异无统计学意义(P>0.05)。结论 pT1期CCRCC的CEUS特点与Fuhrman分级有一定相关性;CEUS可为临床提供更多有价值的信息。
Objective To explore the relationship among CEUS modalities and quantitative parameters of pT1 clear cell renal carcinoma （CCRCC） and pathological Fuhrman grades. Methods CEUS enhancement pattern and quantitative data of 83 patients with pT1 CCRCC confirmed by pathology were retrospectively analyzed. The enhanced pattern, degree, homogeneity, peritumoral hyperenhanced rim （PHR）, as well as arrival time （AT）, time to peak（TTP） and peak intensity （PI） got from time-intensity curve software in different grade tumors were observed and compared with Fuhrman grades. Results In 83 cases, there was significant differences of PHR and △PI among different Fuhrman grades （all P〈0.05）. The PHR detection rate of grade Ⅰ was relatively higher, for which △PI value was lowest, and the PHR detection rate of grade Ⅳ was relatively lower, for which △PI was highest. The homogeneity of enhancement in different grade tumors had no statistical difference （P〉0.05）. CCRCC mainly showed ＂quick in＂ （61/83, 73.49%）, ＂fast out＂ （34/83, 40.96%） and ＂slow out＂ （37/83, 44.58%） modalities, and there was no statistical difference among different grades （P〉0.05）. Conclusion CEUS characteristics of pT1 CCRCC are related to Fuhrman grade, therefore can provide more valuable information.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第10期1711-1714,共4页
Chinese Journal of Medical Imaging Technology
关键词
癌
肾细胞
造影剂
超声造影
Fuhrman分级
Carcinoma, renal cell
Contrast media
Contrast-enhanced ultrasound
Fuhrman grades
