期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

miRNA-34a、Notch1与乳腺癌发生、发展的研究进展 被引量：6

暂未订购
导出
摘要 miRNA-34a在众多肿瘤中发挥作用,通过作用靶基因Notch1调控Notch信号通路,广泛参与肿瘤细胞增殖、侵袭、转移等恶性生物学行为。探讨miRNA-34a-Notch1信号通路在乳腺癌发生、发展中的作用机制,对乳腺癌的防治可能具有重要意义。
作者 万国兴 李锋 孙建平 李文琴 曹玉文
机构地区 石河子大学医学院病理学系 石河子大学新疆地方病与民族高发病教育部重点实验室
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2013年第10期1113-1115,共3页 Chinese Journal of Clinical and Experimental Pathology
基金 国家自然科学基金(30760072)
关键词 乳腺肿瘤 miRNA-34a NOTCH1 文献综述
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献26

  • 1Fabian M R, Sundermeier T R, Sonenberg N. Understanding how miRNAs post-transcriptionally regulate gene expression [ J ]. Prog Mol Subcell Biol, 2010,50 : 1 - 20.
  • 2周凡,庄诗美.microRNA与肿瘤[J].生命科学,2008,20(2):207-212. 被引量：23
  • 3Tarasov V, Jung P, Verdoodt B, et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miRNA-34a is a p53 target that induces apoptosis and G1-arrest [J]. Cell Cycle, 2007,6(13) :1586 -93.
  • 4Kumamoto K, Spillare E A, Fujita K, et al. Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senes- cence[J]. Cancer Res, 2008,68(9) :3193 -203.
  • 5戚艳婷,赵喻,张智,李丹,顾吉轶,付笑男,陈小娜,袁崇刚,赖立辉.mir-34a在神经元中的表达特征及功能研究[J].分子细胞生物学报,2009,42(3):217-223. 被引量：7
  • 6Yan D, Zhou X, Chen X, et al. MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met[ J. Invest Ophthalmol Vis Sci, 2009,50 (4) : 1559 - 65.
  • 7Guruharsha K G, Kankel M W, Artavanis-Tsakonas S. The Notch signalling system: recent insights into the complexity of a con- served pathway [ J ]. Nat Rev Genet, 2012,13 (9) :654 - 66.
  • 8Milner L A, Bigas A. Notch as a mediator of cell fate determina- tion in hematopoiesis: evidence and speculation [ J ]. Blood, 1999,93(8) :2431 -48.
  • 9徐执政,陈苏宁,薛永权.Notchl基因突变与T细胞急性淋巴细胞白血病[J].国际遗传学杂志,2008,31(2):99-102. 被引量：3
  • 10Karsan A. The role of notch in modeling and maintaining the vas- culature [ J ]. Can J Physiol Pharmacol, 2005,83 ( 1 ) : 14 - 23.

二级参考文献127

  • 1许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量：1379
  • 2Kojika S, Griffin JD..Notch receptors and hematopoiesis. Exp Hematol, 2001,29 : 1041-1052.
  • 3Izon DJ, Punt JA, Pear WS. Deciphering the role of Notch signaling in lymphopoiesis. Curr Opin Immunol, 2002,14 : 192-199.
  • 4Logeat F, Bessia C, Brou C, et al. The Notchl receptor is cleaved constitutively by a furin-like convertase. Proc Natl Acad Sci U S A, 1998,95:8108-8112.
  • 5Leong KG, Karsan A, Recent insights into the role of Notch signaling in tumorigenesis. Blood,2006, 107 : 2223- 2233.
  • 6Miele L. Notch signaling. Clin Cancer Res, 2006,12 : 1074-1079.
  • 7Weng AP, Lau A. Notch signaling in T-cell acute lymphoblastic leu- kemia. Future Oncology, 2005, 1 : 511-519.
  • 8Leong KG, Karsan A. Recent insights into the role of Notch signaling in tumorigenesis. Blood,2006, 107 : 2223- 2233.
  • 9Weng AP, Ferrando AA, Lee W, et al. Activating mutations of NOTCHI in human T cell acute lymphoblastic leukemia. Science, 2004,306:269-271.
  • 10Gupta-Rossi N, Le Bail O, Gonen H, et al. Functional interaction between SEL-10; an F-box protein, and the nuclear form of activated Notchl receptor. J Biol Chem, 2001,276:34371-34378.

共引文献55

同被引文献51

  • 1Long X H, Zhang Z H, Liu Z L, et al.Inhibiting valosin-containing protein suppresses osteosarcoma cell metastasis via AKT/nuclear factor of kappa B signaling pathway in vitro[J].Indian J Pathol Microbiol, 2013,56(3):190-5.
  • 2Kim S Y, Helman L J.Strategies to explore new approaches in the investigation and treatment of osteosarcoma[J].Cancer Treat Res, 2009,152:517-28.
  • 3Niswander L M, Kim S Y.Stratifying osteosarcoma: minimizing and maximizing therapy[J].Curr Oncol Rep, 2010,12(4):266-70.
  • 4Munajat I, Zulmi W, Norazman M Z, Wan Faisham W I.Tumour volume and lung metastasis in patients with osteosarcoma[J].J Orthop Surg(Hong Kong), 2008,16(2):182-5.
  • 5Ewens C A, Kloppsteck P, F?rster A, et al.Structural and functional implications of phosphorylation and acetylation in the regulation of the AAA+ protein p97[J].Biochem Cell Biol, 2010,88(1):41-8.
  • 6Wang Q, Song C, Li C C.Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions[J].J Struct Biol, 2004,146(1-2):44-57.
  • 7Lass A, Kujawa M, McConnell E, et al.Decreased ER-associated degradation of alpha-TCR induced by Grp78 depletion with the SubAB cytotoxin[J].Int J Biochem Cell Biol, 2008,40(12):2865-79.
  • 8Livingstone M, Ruan H, Weiner J, et al.Valosin-containing protein phosphorylation at Ser784 in response to DNA damage[J].Cancer Res, 2005,65(17):7533-40.
  • 9Yamamoto S, Tomita Y, Uruno T, et al.Increased expression of valosin-containing protein(p97)is correlated with disease recurrence in follicular thyroid cancer[J].Ann Surg Oncol, 2005,12(11):925-34.
  • 10Yamamoto S, Tomita Y, Hoshida Y, et al.Expression level of valosin-containing protein(p97)is associated with prognosis of esophageal carcinoma[J].Clin Cancer Res, 2004,10(16):5558-65.

引证文献6

二级引证文献13

临床与实验病理学杂志
2013年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部