摘要
在急性心肌缺血模型上观察侧脑室微量注射去甲肾上腺素对心肌缺血的影响以及侧脑室注射酚妥拉明和心得安对电针“内关”心脏效应的影响。结果 :去甲肾上腺素使心肌缺血恢复变慢 ,电针“内关”则能加快心肌缺血的恢复 ;酚妥拉明阻断电针“内关”的效应 ,而心得安不对抗电针的效应。提示中枢肾上腺素能系统参与电针“内关”的心脏效应 ,电针“内关”可能通过兴奋α受体、抑制β受体兴奋起作用。
The effect of lateral cerebroventricular microinjection of norepinephrine(NE) on acute myocardial ischemia (AMI) and the influence of lateral cerebroventricular microinjection of phentolamine or propranolol on the effect of electroacupuncture (EA) of “Neiguan”(PC 6)in improving AMI were observed in 49 rabbits. The results showed that: (1) lateral cerebroventricular microinjection of NE could slow down the recovery of AMI; (2)EA of “Neiguan”(PC 6) could accelerate the recovery of AMI; (3) lateral cerebroventricular microinjection of phentolamine abolished the effect of EA, but propranolol did not. The facts suggest that central adrenergic system participates in the action of EA at “Neiguan”in ameliorating AMI. EA of “Neiguan” plays its role probably by way of activating central α receptors and inhibiting central β receptors.
出处
《针刺研究》
CAS
CSCD
2000年第4期263-266,共4页
Acupuncture Research
基金
广东省自然科学基金!资助项目 (No.930 40 0 )