摘要
目的调查我院医院感染的病原菌构成与耐药情况。方法选择2012年1—12月在我院发生的医院感染患者300例为研究对象，分离痰液进行细菌培养与耐药分析。结果分离得到160株病原菌，阳性率为53．3％，主要细菌为铜绿假单胞菌、真菌、大肠埃希菌、肺炎克雷伯菌等。头孢哌酮／舒巴坦、头孢他啶与亚胺培南对铜绿假单胞菌、大肠埃希菌和肺炎克雷伯菌的耐药性比较好，而复方新诺明、头孢唑林与氯霉素的耐药性都相对比较差。结论医院感染已经成为患者安全的严重威胁，本院医院感染的病原菌主要为铜绿假单胞菌、真菌、大肠埃希菌，要根据耐药结果合理选择抗菌药物。
Objective To investigate the situation of pathogenic bacteria and drug resistance of hospital infection in our hospital. Methods 300 cases of hospital infection in our hospital were selected from January 2012 to December 2012 as the research objects,there were separated the sputum for bacterial culture and given the drug resistance analysis. Results There were separated 160 pathogenic bacteria,the positive rate was 53.3%,the main bacterials were the Pseudomonas aeruginosa,Fungi,Escherichia coli,pneumonia Klebsiella monocytogenes.The drug resistance of Cefoperazone/sulbactam,ceftazidime and imipenem had relatively better drug resistance,and the cotrimoxazole,cefazolin and chlorine mycophenolate had relatively poor drug resistance. Conclusion The hospital infection has become the serious threat for patient safety,My hospital infection＇s pathogens are mainly Pseudomonas aeruginosa, fungi and Escherichia coli,we should accord to drug-resistant results to select the reasonableantimierobial drugs.
出处
《中国医药科学》
2013年第19期83-84,共2页
China Medicine And Pharmacy
关键词
医院感染
病原菌
耐药分析
Hospital infection
Pathogenic bacteria
Drug resistance analysis
