摘要
目的:探讨稳定型冠心病(SCHD)患者静脉血浆B型利钠肽(BNP)水平与中远期住院事件的关系。方法:入选88例老年SCHD患者,均经冠脉造影(CAG)证实。按所测定的静脉BNP浓度分为BNP≥108pg/ml组(44例)和BNP<108pg/ml组(44例)。随访两组5年的死亡、非致死性ACS、再次PCI等心血管原因和非心血管原因住院事件,并进行比较。结果:平均随访62.7月,高水平BNP组的全因住院事件率显著高于低水平BNP组[62.1%(141/227)比37.9%(86/227),P=0.041],非心血管原因住院率非常显著高于低水平BNP组[39.2%(89/227)比16.3%(37/227),P=0.010]。结论:老年稳定型冠心病中基线B型利钠肽水平较高者的远期住院事件率较高。
Objective： To explore relationship between venous plasma level of B type natriuretic peptide （BNP） and medium-long term hospitalization events in aged patients with stable coronary heart disease （SCHD）. Methods： A total of 88 aged SCHD patients proved by coronary angiography （CAG） were enrolled. According to their venous BNP concentrations, they were divided into BNP≥108pg/ml group （n = 44） and BNP〈108pg/ml group （n = 44）. Rates of hospitalization events within five years, including cardiovascular-cause hospitalization （death, nonfatal a- cute coronary syndrome, second percutaneous coronary intervention） and non cardiovascular-cause hospitalization, were followed up. Results： After a mean 62.7 months follow-up, rate of all-cause hospitalization events of high BNP level group [62.1% （141/227）] were significantly higher than that of low BNP level group [37.9% （86/ 227）, P = 0. 041], especially rates of non cardiovascular-cause hospitalization events [39.2% （89/227） vs. 16.3% （37/227）, P = 0. 010]. Conclusion： Rates of medium-long term hospitalization events are higher in aged patients with stable coronary heart disease who have high baseline level of B type natriuretic peptide.
出处
《心血管康复医学杂志》
CAS
2013年第5期454-457,共4页
Chinese Journal of Cardiovascular Rehabilitation Medicine
基金
上海市浦东新区卫生局重点协作项目(PW2010D-9)
关键词
冠状动脉疾病
利钠肽
脑
住院
Coronary artery disease
Natriuretic peptide, brain
Hospitalization
