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多重心血管危险因素患者踝臂指数与颈动脉内膜中层厚度的相关性研究

Correlation between Carotid Intima-Media Thickness and Ankle-Brachial Index in Patients with Multiple Cardiovascular Risk Factors
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摘要 目的探讨老年合并心血管危险因素人群踝臂指数(ABI)与颈动脉内膜-中层厚度(IMT)的关系。方法选择160例老年合并心血管危险因素人群为观察组,按合并危险因素个数分为3组,30例健康体检人员为对照组,同时进行ABI及颈动脉血管超声检查,检测血脂、血糖。结果观察组ABI为0.85±028,明显低于对照组1.19±0.25,差异有统计学意义(P<0.01)。随着危险因素增加,ABI呈下降趋势,IMT呈增厚趋势;ABI与IMT呈负相关(r=-0.35,P<0.05)。结论在老年心合并心血管危险因素人群中,ABI可作为动脉硬化的常规筛查手段。 Objective To study the relationship between carotid intima- media thickness and ankle- brachial index (ABI) in elderly patients with multiple cardiovascular risk factors (RFs). Methods 160 elderly patients with multiple car-diovascular RFs were divided into 3 groups based on the numbers of RFs and compared with 30 healthy subjects. ABI measurements and carotid ultrasonography were performed. Blood lipid and glucose were measured. Results ABI was significantly lower in patients than in healthy subjects (0.85 ±0.28 vs 1.19 ±0.25,P〈0.01). ABI decreased and IMT in-creased as RFs increased. ABI was negatively correlated with IMT (r=- 0.35,P〈0.05). Conclusion ABI can be used to evaluate atherosclerosis in elderly patients with multiple cardiovascular RFs.
出处 《心电与循环》 2013年第5期390-392,共3页 Journal of Electrocardiology and Circulation
基金 浙江省海盐县科技计划重点项目(2012Y3B1001)
关键词 踝臂指数 颈动脉内膜-中层厚度 心血管危险因素 Ankle-brachial index Carotid intima-media thickness Cardiovascular risk factor
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