摘要
糖皮质激素因其有效的抗炎和免疫抑制作用,已成为风湿免疫病治疗的基础用药,但又存在很多副反应,因此合理有效应用糖皮质激素成为临床医师关注的热点。目前在风湿免疫病中以应用中效糖皮质激素为主。此外,糖皮质激素的治疗需遵循个体化的原则,起始剂量、如何减量以及长期维持量取决于所患风湿免疫病种类、疾病活动程度、出现不良反应的危险因素以及患者的个体反应性。
The glucocorticoid has become the anchor drug for the treatment of rheumatic diseases because of its potent anti- inflammatory and immunosuppressive effect. Glucocorticoid treatment could result in numerous side effects, so effective and appropriate treatment with glucocorticoid is very important in clinical practice. Middle-effect glucocorticoid was the most common type used in rheumatic disease, and glucocorticoid treatment should be individualized in each patient. Initial dos- age, tapering method, and maintenance dosage depends on the types of rheumatic diseases, degree of disease activity, risk of side effect, and patient response to treatment.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2013年第10期775-778,共4页
Chinese Journal of Practical Internal Medicine
关键词
糖皮质激素
风湿免疫病
免疫抑制
glucocorticoid
rheumatic disease
immunosuppression
