摘要
目的分析胰十二指肠切除术（PD）术后并发症的相关危险因素。方法回顾性分析安徽省立医院2007年12月至2012年12月收治的207例行PD患者的临床资料，选择17个可能对PD后并发症发生率产生影响的非重复特征性临床因素进行分析。结果PD术后并发症单因素分析提示：有无基础疾病、是否行术前减黄、术前血清总胆红素水平、术前丙氨酸转氨酶水平、术前血清白蛋白水平、术前血清前白蛋白水平、胰腺质地以及主胰管直径对PD术后并发症的发生率有影响（P〈0．05）。多因素分析提示：PD术后并发症独立危险因素为术前血清丙氨酸转氨酶水平、胰腺质地及胰管直径（P〈0．05）。术后胰瘘的独立危险因素为胰管直径（〈3mm）；术后出血独立危险因素为胰瘘。结论影响PD术后并发症的危险因素为术前血清丙氨酸转氨酶水平、胰腺质地及胰管直径。
Objective To investigate the risk factors of post-pancreaticoduodenectomy complications. Methods The clinical data of 207 patients with pancreatic carcinoma or peri-ampullary carcino- ma who underwent pancreaticoduodenectomy at the Anhui Provincial Hospital from Dec. 2007 to Dec. 2012 were studied. Seventeen clinicopathologic factors to correlate with the postoperative mortality and methods were selected for univariate analysis and multivariate analysis using logistic regression. Results Univariate analysis showed the major risk factors of postoperative mortality and morbidity were a history of previous operation, pre-operative drainage, total serum bilirubin level, aianine amin- otransferase level, serum albumin level, serum pre-albumin level, parenchyma texture and pancreatic duct diameter （P〈0.05）. Multivariate analysis showed alanine aminotransferase level, parenchyma texture and pancreatic duct diameter were independent risk factors of postoperative complications. Pancreatic duct diameter was the independent risk factor of pancreatic fistula. Pancreatic fistula was the independent risk factor of hemorrhage. Conclusion The postoperative complications of pancreaticoduodenectomy was closely related to alanine aminotransferase level, parenchyma texture and pancreatic duct diameter.
出处
《中华肝胆外科杂志》
CAS
CSCD
北大核心
2013年第9期691-695,共5页
Chinese Journal of Hepatobiliary Surgery
