摘要
目的研究维生素D对COPD患者肺功能及生活质量的影响。方法采用随机抽样的方法,抽取近1年在我院治疗的COPD患者90例,以及同院体检的健康体检者38例作为研究对象。比较不同COPD严重程度及对照组研究对象的血清25-(OH)D水平、维生素D缺乏患病率的差异以及维生素D缺乏对患者CAT问卷评分的影响。结果COPD急性加重组与COPD稳定组的血清25-(OH)D水平低于对照组(P<0.05),且COPD急性加重期低于COPD稳定组(P<0.05);COPD急性加重组的维生素D缺乏症病率高于COPD稳定组与对照组(P<0.01);维生素D缺乏患者CAT问卷评分较高(P<0.05)。结论缺乏维生素D可导致COPD患者肺功能降低及生活质量下降,临床上应注意对COPD患者补充维生素D。
Objective To study the influence of Vitamin D to the pulmonary function and living quality in COPD patients.Methods By using the randomized sampling method,90 COPD patients who treated in our hospital and 38 healthy controls were sampled.To compare the difference of the 25-（OH）D level in serum,the prevalence rate of Vitamin D deficiency and the influence of Vitamin D deficiency to the score of CAT scale in patients among the patients with different COPD level and control group.Results The acute exacerbation of COPD group and the stable phase of COPD group had a lower 25-（OH）D level in serum than the control group（P0.05）.And the acute exacerbation of COPD group had a lower 25-（OH）D level in serum than the stable phase of COPD group（P0.05）.The acute exacerbation of COPD group had a higher prevalence rate of Vitamin D deficiency than the stable phase of COPD group and the control group（P0.01）.The Vitamin D deficiency patients had a higher score of CAT scale（P 0.05）.Conclusion The deficiency of Vitamin D may cause reduced lung function and life quality drops in the COPD patients.So the Vitamin D supplement should be paid attention to the clinical treatment for COPD.
出处
《江西医药》
CAS
2013年第8期668-670,共3页
Jiangxi Medical Journal
