摘要
目的:观察中国蛤蜊精(每100g中,含多糖19.01g、牛磺酸1.25g、胆碱0.65g)对小鼠免疫功能的影响。方法:用中国蛤蜊精按0.5、1.5、3.0g/(kg·d)的剂量对小鼠灌胃,连续10d,测定小鼠白细胞总数及分类计数、通过抗体凝集反应实验测定效价、测定抗体生成细胞水平、腹腔巨噬细胞吞噬功能、体质量变化及免疫器官质量,并对其结果进行统计分析。结果:与生理盐水组(对照组)相比,中国蛤蜊精各剂量组淋巴细胞相对数、抗体生成水平、抗体生成细胞水平、小鼠腹腔巨噬细胞吞噬功能和脾脏指数均显著升高(P<0.05)。结论:中国蛤蜊精有显著增强小鼠免疫功能的作用。
Objective： To observe the immunoregulatory effect of Mactra chinensis meat extract （EMC, containing 19.01 g of polysaccharide, 1.25 g of taurine and 0.65 g of choline /100 g） in mice. Methods： Mice were orally administered with EMC at doses of 0.5, 1.5, 3.0 g/（kg？d） for 10 d. A series of immune function indices such as the total number and classification of white blood cells （WBC）, the titer of antibody production in agglutination reaction and the quantity of plaque-forming cells （PFC）, macrophage phagocytosis test, and the weight of body and immune organs were analyzed. Results： Compared with the control group, the relative number of lymphocytes, the activity of antibody production, the quantity of antibody-forming cells, the phagocytic function of mouse peritoneal macrophages and the index of spleen in all the treated groups were improved significantly （P 〈0.05）. Conclusion： EMC enhances the immune activity of normal mice effectively.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2013年第17期305-308,共4页
Food Science
基金
山东省科技厅星火计划项目(2011SH05012)
关键词
中国蛤蜊精
细胞免疫
体液免疫
非特异性免疫
water extract from Mactra chinensis （EMC）
cellular immunity
humoral immunity
nonspecific immunity
