摘要
目的探讨ICU患者血培养阳性的临床特征、感染危险因素及药敏结果。方法回顾性分析ICU 2007年7月-2012年1月住院患者血培养阳性临床特征及病原学资料,参照卫生部制定的医院感染诊断标准;计数资料用Excel软件进行统计描述分析,相对数主要用率和构成比表示,采用χ2检验进行分析研究。结果在50例血培养阳性的患者中有中心静脉导管及有创侵入性操作占100.0%,有手术史10例,气管插管或气管切开47例,基础疾病以多发伤20例为最多占40.0%,其次多器官功能衰竭14例占28.0%,死亡7例占14.0%,鲍氏不动杆菌居首位占34.0%,对头孢哌酮/舒巴坦、万古霉素、亚胺培南的敏感性较高,对阿米卡星敏感性为41.0%,其次为表皮葡萄球菌占26.0%、溶血葡萄球菌占8.0%。结论由于ICU患者病情严重、有创操作多、感染的危险因素多、多种因素影响菌种在体内的定植和感染,应高度重视并加以防范感染的发生,同时加强基础疾病的治疗,减少不必要的侵入性操作,感染防范仍需长期监测。
OBJECTIVE To explore the clinical characteristics risk factors of infections,and the drug susceptibilityof the patients with positive blood culture. METHODS Retrospective analysis of the clinical and microbiological da-ta of the ICU hospitalized patients with positive blood cultures from Jul 2007 to Jan 2012 in the hospital was performed with reference to the nosocomial infection diagnostic criteria prepared by Ministry of Health. The descriptive analysis of count data was performed by using Excel software. The relative numbers were expressed by therate and constituent ratio and analyzed using χ^2 test. RESULTS Among 50 patients with positive blood culture, allof them were subjected to the central venous catheter and invasive procedures; 10 cases of them had the operationhistory, 47 cases of them had undergone endotracheal intubation or tracheotomy. For the basic diseases,the patients with multiple-trauma were the most, 20 cases, accounting for 40. 0%,14 cases with multi-organ failure,ac-counting for 28. 0%,and 7 cases died, accounting for 14. 0%. The Acinetobacter baumannii strains accounted for34. 0% , which were highly sensitive to cefoperazone-sulbactam, vancomycin, imipenem and 41. 0% of patientswere sensitive to amikacin. The Staphylococcus epidermidisstrains accounted for 26. 0%,and the taphylococcushaemolyticusstrains accounted for 8. 0？. CONCLUSION Since the conditions of the ICU patients are serious, theinvasive operation is frequent, and the risk factors are complex, these factors will affect the planting and infectionof the strains, so it is necessary to attach great importance to the prevention of the occurrence of the infections;besides, it is necessary to strength the treatment of basic diseases,to minimize unnecessary invasive procedures. Along-term monitoring of the infection prevention should be strengthened.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第17期4317-4318,共2页
Chinese Journal of Nosocomiology
关键词
血培养
药敏试验
危险因素
Blood culture
Drug sensitivity test
Risk factor
