摘要
目的:观察参竹心康汤对慢性心力衰竭(简称"心衰")患者心功能与生活质量的影响。方法:将91例慢性心衰患者随机分为治疗组46例与对照组45例。对照组以西医常规治疗,治疗组在对照组治疗基础上加服参竹心康汤。观察Lee氏心力衰竭计分、中医证候、生活质量、6min步行试验,采用高分辨率超声技术检测左室射血分数(LVEF)、二尖瓣舒张早期流速峰值(EPFV)、二尖瓣舒张晚期流速峰值(APFV)及二者之比(E/A)。结果:两组患者上述各项指标均有明显改善,且治疗组在心力衰竭及中医证候疗效、心功能指标、生活质量及6min步行距离等方面优于对照组,差异有统计学意义(P<0.05或P<0.01)。结论:参竹心康汤可提高慢性心衰患者的临床疗效,改善患者心功能和生活质量。
Objective ：To observe the effects of Shenzhu Xinkang decoction on the cardiac function and quality of life （QOL） in patients with chronic heart failure （CHF）. Methods ：Ninety -one CHF patients were randomly di vided into treatment group （n = 46） and control group （n = 45 ）. The control group received conventional West ern medicine treatment,while the treatment group received Shenzhu Xinkang decoction in addition to conventional Western medicine treatment. The therapeutic effects were assessed based on Left heart failure score, traditional Chi nese medicine （TCM） syndrome, QOL, and six - minute walk test. In addition, left ventricular ejection fraction, ear ly peak filling velocity （ EPFV）, atrial peak filling velocity （ APFV）, and the ratio of EPFV to APFV were measured by high -resolution ultrasound. Results：Both groups showed significant improvements in the above indices, and the treatment group was superior to the control group in terms of the outcomes of CHF and TCM syndrome, cardiac func- tion indices, QOL, and six - minute walk distance （ P 〈 0.05 or P 〈 0.01 ）. Conclusion ： Shenzhu Xinkang decoction can improve treatment outcome,cardiac function,and QOL in CHF patients.
出处
《湖南中医杂志》
2013年第9期9-12,共4页
Hunan Journal of Traditional Chinese Medicine
基金
湖南省中医药科研计划资助项目(编号:2009041)
关键词
慢性心衰
中医药疗法
参竹心康汤
chronic heart failure
traditional Chinese medicine treatment
Shenzhu Xinkang decoction
