摘要
目的探讨鼻窦颅底神经内分泌癌经内镜鼻窦颅底一期手术的早期疗效。方法对5例鼻窦颅底神经内分泌癌经内镜鼻窦颅底一期手术治疗病人的临床资料进行回顾性分析。结果 5例病人中,除1例肺大细胞神经内分泌转移癌病人,术后4个月死于脑梗死外,其余4例病人生存6～32月,中位生存期18个月。结论内镜经鼻腔鼻窦颅底神经内分泌癌的微创手术治疗是有效可行的,且可提高病人术后的生存质量;鼻窦颅底神经内分泌癌病人经内镜鼻窦颅底手术后近期易发生脑梗死等相关颅内并发症,应予以高度重视和预防处置。
Objective To investigate the early therapeutic effect of transnasal endoscopic surgery for nasal skull base neuroendocrine carcinoma. Methods A retrospective review was performed of five patients underwent one-stage transnasal endo- scopic surgery for nasal-skull base neuroendocrine carcinoma with regard to its early curative effect. Results Of the five patients, excepted one died of cerebral infarction 4 months after operation, the other four still survived up to the last follow-up, with the live time （mean） of 6--32 （18） months. Conclusion Transnasal endoscopic minimally-invasive surgery for nasal-skull base neuroen- docrine carcinoma is effective and feasible, and improves patient＇s quality of survival as well. Postoperative brain-infarction related intracranial complications are prone occur, to which a great attention and prevention should be paid.
出处
《齐鲁医学杂志》
2013年第6期482-484,共3页
Medical Journal of Qilu
关键词
颅底肿瘤
神经内分泌癌
内窥镜检查
治疗结果
skull base neoplasms
neuroendocrine carcinoma
endoscopy
treatment outcome
