摘要
目的采用循证医学Meta分析的方法探讨银离子敷料联合水凝胶治疗糖尿病足的有效性。方法计算机检索CochraneLibrary、EMbase、中国学术期刊全文数据库（CNKI）、中文科技期刊全文数据库（VIP）、万方数据库，检索关于银离子敷料联合水凝胶治疗糖尿病足的临床随机对照实验文献。采用RevMan5．0软件进行Meta分析，评价银离子敷料联合水凝胶治疗糖尿病足的效果。结果共纳入11篇临床对照研究，包括765例糖尿病足患者。Meta分析结果表明：银离子敷料联合水凝胶组患者足部治疗有效率显著高于对照组，银离子敷料联合水凝胶组患者肉芽组织生长时间明显低于对照组，银离子敷料联合水凝胶组患者上皮形成时间与对照组比较差异无统计学意义，银离子敷料联合水凝胶组患者足部基本愈合时间显著低于对照组。结论银离子敷料联合水凝胶治疗糖尿病足有效率高，且肉芽组织生长时间短，足部愈合时间短。由于纳入研究质量及数量有限，本研究结论尚需大样本高质量临床研究进行证实。
Objective To evaluate the therapeutic effect of silver ion dressings combined with hydro gel in treatment of diabetic foot by using Meta-analysis. Methods The Cochrane Library, EMbase and domestic main databases were searched,the quality of included studies which screened by certain standards was evaluated. The Review Manager 5.0 software was taken for analysis. Results Totally 11 studies were included, containing 765 patients with diabetic foot. The Meta-analysis showed that there were significant dif- ferences between two groups in treatment eglciency, granulation tissue growth time and basic healing time. But the epithelial formation time showed no significant difference between two groups. Conclusions Silver ion dressings combined with hydro gel in treatment of diabetic foot was effective. However,the quality and quantity of most studies included in this review are low, studies of higher quality and quantity are needed to confirm the results in the future.
出处
《中国实用护理杂志》
北大核心
2013年第29期17-21,共5页
Chinese Journal of Practical Nursing
基金
江苏省自然科学基金项目（BK2012651）
