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纳米材料改性脱细胞猪真皮基质的研究 被引量:2

Porcine Acellular Dermal Matrix Modified with Nanomaterials
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摘要 将纳米SiO2、纳米TiO2及纳米银的溶液与脱细胞猪真皮基质(porcine acellular dermal matrix,pADM)复合,考察改性前后材料的表面微观结构、收缩温度、抗张强度、透水汽性、孔隙率和抗菌性能。研究结果表明:纳米材料能以纳米粒子状态较好地分布于pADM内,随着纳米SiO2、纳米TiO2用量的增大,改性后的pADM收缩温度提高,抗张强度提高,孔隙率增大,透水汽性提高,对大肠杆菌和金黄色葡萄球菌具有良好的抗菌效果;纳米银改性后的pADM收缩温度降低,抗张强度增大,孔隙率减小,透水汽性略有减小,对大肠杆菌和金黄色葡萄球菌具有优良的抗菌效果。 Porcine acellular dermal matrix were compounded with nano-SiO2, nano-TiO2 and nano-silver. The surface mi- erostructure, shrinkage temperature, tensile strength, water vapor permeability, porosity and antimicrobial properties of the materials before and after modification were all characterized. The results show that nanoparticles can be well distributed inside the eollagenous fibers in nano scale. As the dosage of nano-SiO2 and nano-TiO2 increases, the shrinkage tempera- ture, tensile strength, porosity and permeability all increased, and composite materials have a good antibacterial effect a- gainst Es.cherichia eoli and Staphylococcus aureus; As the dosage of nano-Ag increases the tensile strength of nano-Ag- pADM increases, its shrinkage temperature, porosity and permeability decreases, and composite materials have a excellent antibacterial effect against Escheriehia coli and Staphylococcus aureus.
出处 《皮革科学与工程》 CAS 北大核心 2013年第5期5-9,共5页 Leather Science and Engineering
基金 四川大学青年教师科研启动基金项目(项目编号:2011SCU11102) 四川大学"大学生创新创业训练计划"校级项目(20130520)
关键词 纳米材料 脱细胞真皮基质 改性 抗菌 nanomaterials porcine acellular dermal matrix modified antibacterial
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