摘要
目的探讨声脉冲辐射力(ARFI)弹性成像的声触诊组织成像(VTI)和声触诊组织定量(VTQ)技术在鉴别诊断甲状腺良、恶性结节中的价值。资料与方法分析85例甲状腺肿瘤患者共100个结节的常规超声及ARFI成像特征,采用常规超声半定量评分法判断结节性质,ARFI成像获取病灶的VTI面积比、剪切波速度(SWV)及SWV比值;采用ROC曲线比较常规超声、VTI面积比、SWV和SWV比值的曲线下面积(AUC),确定诊断效能。结果常规超声半定量法诊断甲状腺良、恶性病灶的准确度、敏感度、特异度分别为82.00%、53.33%、94.29%;良、恶性病灶平均VTI面积比分别为1.11±0.12、1.65±0.35(t=11.524,P<0.01),平均SWV分别为(1.84±1.00)m/s、(4.93±2.94)m/s(t=7.840,P<0.001),平均SWV比值分别为1.07±0.44、2.81±1.72(t=7.910,P<0.001);ROC曲线得出常规超声、VTI面积比、SWV、SWV比值的AUC分别为0.889、0.948、0.933、0.896,VTI面积比诊断甲状腺良、恶性病灶的准确度、敏感度、特异度分别为90.00%、93.33%、88.57%,SWV的诊断准确度、敏感度、特异度分别为88.00%、90.00%、87.14%,SWV比值的诊断准确度、敏感度、特异度分别为88.00%、70.00%、95.71%。结论ARFI弹性成像有助于鉴别甲状腺结节的良、恶性,提高诊断敏感度。
Purpose To explore the value of virtual touch tissue imaging （VT1） and virtual touch tissue quantification （VTQ） technology of acoustic radiation force impulse （ARFI） elastography in the differential diagnosis of benign and malignant thyroid nodules. Materials and Methods The routine ultrasound （US） and ARFI imaging features of 100 nodules in 85 patients with thyroid cancer were analyzed. Nodules were evaluated according to US semi-quantitative score; VT1 area ratio, shear wave velocity （SWV） and SWV ratios were obtained by ARFI： then receiver operating characteristic （ROC） curves were drawn to compare the areas under the curves （AUC） of routine US, VTI area ratio, SWV and SWV ratios to evaluate diagnostic accuracy. Results The accuracy, sensitivity and specificity of benign and malignant thyroid lesions were 82.00%, 53.33%, and 94.29%, respectively on routine US score. Mean VTI ratios： 1.11＋0.12 for benign nodules, 1.65± 0.35 for malignant nodules （t- 11.524, P〈0.01 ）; SWVs： （ 1.84± 1.00） m/s for benign nodules, （4.93±2.94） m/s for malignant nodules （t=7.840, P〈0.001）; mean SWV ratios： 1.07±0.44 for benign nodules, 2.81±1.72 for malignant nodules （t-7.910, P〈0.001）. ROC analysis indicated that AUC was 0.889 for semi-quantitative scores, 0.948 for VTI area, 0.933 for SWV and 0.896 for SWV ratio. The accuracy, sensitivity, specificity of VTI area were 90.00%, 93.33% and 88.57%, respectively： those of SWV were 88.00%, 90.00% and 87.14%, respectively; those of SWV ratio were 88.00%, 70.00% and 95.71%, respectively. Conclusion ARFI elastography is helpthl in differentiating benign and malignant thyroid nodules for a high diagnostic sensitivity.
出处
《中国医学影像学杂志》
CSCD
北大核心
2013年第9期688-692,共5页
Chinese Journal of Medical Imaging
关键词
甲状腺结节
超声检查
弹性成像技术
声触诊组织成像
声触诊组织定量技术
诊断
鉴别
Thyroid nodule
Ultrasonography
Elasticity imaging techniques
Virtualtouch tissue imaging
Virtual touch tissue quantification
Diagnosis, differential
