摘要
目的研究使用小剂量多巴胺治疗新生儿重度窒息的临床效果,为临床实践提供一定的理论依据。方法将54例重度新生儿窒息的患者随机分成两组,其中一组为对照组27例。对患者在窒息复苏之后使用吸氧、降低患者颅内压、维持脑的灌注,控制对于患者的入液,保持患者体内酸碱平衡。另一组为治疗组27例,该组患者在对照组治疗的基础之上,在早期使用小剂量的多巴胺对患者开展治疗。对治疗之后对两组患者的治疗效果进行对比。结果两组患者相比较,患者心功能损害发生的情况无显著性差异,但是胃肠障碍和肾功能的损害发生率降低有着显著的统计学差异。结论早期小剂量多巴胺治疗重度窒息的患者可以有效的减少患者胃肠以及肾脏等一些重要器官的损害,从而最大限度的缓解患者的病情,缩短患者治疗的病程,提升患儿的治愈率,值得在临床上进行应用推广。
Objective to study the use of small doses of dopamine in the treatment of neonatal severe asphyxia, provide certain theoretical basis for clinical practice. Methods The 54 cases of severe neonatal asphyxia were randomly divided into two groups, one group was the control group of 27 patients. After resuscitation for patients using oxygen, reducing intracranial pressure in patients maintain cerebral perfusion, control lfuid into the patient, the patient's body to maintain acid-base balance. Another group of 27 patients for the treatment of the patients in the control group on the basis of the treatment in the early use of small doses of dopamine on patients to carry out treatment. After the treatment the therapeutic effect of two groups of patients were compared. Results Compared two groups of patients, cardiac dysfunction happens no signiifcant difference, but gastrointestinal disorders and kidney damage has reduced the incidence of signiifcant statistical difference . Conclusion Early treatment of low-dose dopamine in patients with severe asphyxia can effectively reduce the number of patients with gastrointestinal and kidney damage to vital organs, thus maximizing ease the patient's condition, shorten the patient's course of treatment to improve the cure rate in children, it is worth the on the clinical application and promotion.
出处
《中国医药指南》
2013年第25期332-332,334,共2页
Guide of China Medicine
关键词
小剂量多巴胺
新生儿窒息
效果分析
Small dose dopamine
Neonatal asphyxia
Effect analysis