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冠心病患者血清叶酸水平的临床意义

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摘要 目的:观察冠心病、高血压病患者及与血清叶酸水平、同型半胱氨酸水平、丙二醛水平及不同患者FMD水平的差别及相关性。方法:选择冠心病患者65例,高血压病患者30例,对照组患者20例,检测血清叶酸水平、同型半胱氨酸水平、丙二醛水平及不同患者FMD水平,比较其差别并进行相关性分析。结果:冠心病患者及高血压病患者血清同型半胱氨酸水平均高于对照组患者,但两组之间差异无统计学意义;冠心病组患者血清叶酸水平低于高血压病患者,而高血压病患者血清叶酸水平低于对照组患者,三组之间血清丙二醛水平呈相反趋势,而FMD水平呈相同趋势;冠心病组患者血清叶酸水平与丙二醛水平呈负相关,与FMD水平呈正相关。结论:低血清叶酸水平是冠心病的一种危险因素,其危害可能与氧化应激有关,而这种危害可能与血清同型半胱氨酸水平无关。
出处 《亚太传统医药》 2013年第9期113-115,共3页 Asia-Pacific Traditional Medicine
基金 广东省科技厅社会引导发展项目(2011B031800011)
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